CAS 152-58-9|Cortodoxone

Introduction:Basic information about CAS 152-58-9|Cortodoxone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameCortodoxone
CAS Number152-58-9Molecular Weight346.461
Density1.2±0.1 g/cm3Boiling Point524.5±50.0 °C at 760 mmHg
Molecular FormulaC21H30O4Melting Point205-208 °C
MSDSUSAFlash Point285.1±26.6 °C
Symbol
GHS02, GHS06, GHS08
Signal WordDanger

Names

Name11-deoxycortisol
SynonymMore Synonyms

Chemical & Physical Properties

Density1.2±0.1 g/cm3
Boiling Point524.5±50.0 °C at 760 mmHg
Melting Point205-208 °C
Molecular FormulaC21H30O4
Molecular Weight346.461
Flash Point285.1±26.6 °C
Exact Mass346.214417
PSA74.60000
LogP2.74
Vapour Pressure0.0±3.1 mmHg at 25°C
Index of Refraction1.578
InChIKeyWHBHBVVOGNECLV-OBQKJFGGSA-N
SMILESCC12CCC(=O)C=C1CCC1C2CCC2(C)C1CCC2(O)C(=O)CO
Storage condition-20°C Freezer

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TU5011500
CHEMICAL NAME :
Pregn-4-ene-3,20-dione, 17,21-dihydroxy-
CAS REGISTRY NUMBER :
152-58-9
BEILSTEIN REFERENCE NO. :
2511358
LAST UPDATED :
199703
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C21-H30-O4
MOLECULAR WEIGHT :
346.51
WISWESSER LINE NOTATION :
L E5 B666 OV MUTJ A1 E1 FV1Q FQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Human Liver
DOSE/DURATION :
2 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 370,49,1996

Safety Information

Symbol
GHS02, GHS06, GHS08
Signal WordDanger
Hazard StatementsH225-H301 + H311 + H331-H370
Precautionary StatementsP210-P260-P280-P301 + P310-P311
Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard CodesF,T
Risk PhrasesR22;R24/25
Safety PhrasesS24/25-S22
RIDADRUN1230 - class 3 - PG 2 - Methanol, solution
RTECSTU5011500

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Synonyms

11-deoxy-17-hydroxy-Corticosterone
CORTEXOLONE
17-Hydroxy-11-desoxy-corticosterone
SK&F 3050
4-Pregnene-17α,21-diol-3,20-dione
17-(1-Keto-2-hydroxyethyl)-4-androsten-17a-ol-3-one
11-Deoxycortisol
11-deoxy-Cortisol
17α,21-Dihydroxy-4-pregnene-3,20-dione
11-dioxy-cortiso
Reichstein S
17,21-Dihydroxyprogesterone
17,21-Dihydroxypregn-4-ene-3,20-dione
Pregn-4-ene-3,20-dione, 17,21-dihydroxy-
Reichstein's substance S
11-Desoxycortisone
Cortodoxone
11-Desoxycortisol
Reichstein's "Substance S"
17-Hydroxy-11-deoxycorticosterone
4-Pregnene-17a,21-diol-3,20-dione
Cortisol, 11-deoxy-
17,21-Dihydroxy-4-pregnene-3,20-dione
11-Deoxy-17-hydroxycorticosterone
17-hydroxydesoxycorticosterone
11-dioxycortisol
EINECS 205-805-2
Corticosterone, 11-deoxy-17-hydroxy-
17,21-Dihydroxy-pregn-4-ene-3,20-dione
skf3050
MFCD00003662
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