CAS 42753-75-3|Methyl 5-amino-2-hydroxybenzoate

Introduction：Basic information about CAS 42753-75-3|Methyl 5-amino-2-hydroxybenzoate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles2
7. Synonyms

Common Name	Methyl 5-amino-2-hydroxybenzoate
CAS Number	42753-75-3	Molecular Weight	167.162
Density	1.3±0.1 g/cm3	Boiling Point	319.2±27.0 °C at 760 mmHg
Molecular Formula	C₈H₉NO₃	Melting Point	95-99 °C(lit.)
MSDS	ChineseUSA	Flash Point	146.8±23.7 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	Methyl 5-amino-2-hydroxybenzoate
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	319.2±27.0 °C at 760 mmHg
Melting Point	95-99 °C(lit.)
Molecular Formula	C₈H₉NO₃
Molecular Weight	167.162
Flash Point	146.8±23.7 °C
Exact Mass	167.058243
PSA	72.55000
LogP	0.56
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.606
InChIKey	MXUHMQZOATZRIK-UHFFFAOYSA-N
SMILES	COC(=O)c1cc(N)ccc1O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VO1683100

CHEMICAL NAME :: Salicylic acid, 5-amino-, methyl ester

CAS REGISTRY NUMBER :: 42753-75-3

BEILSTEIN REFERENCE NO. :: 2803211

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H9-N-O3

MOLECULAR WEIGHT :: 167.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 61,255,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 61,255,1965

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H317-H319-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn
Risk Phrases	22-36/37/38-43
Safety Phrases	S26
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	VO1683100
HS Code	2922509090

Customs

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles2

[Therapeutic effect of methyl 5-aminosalicylate on experimental ulcerative colitis in rabbits].

Zhongguo Yao Li Xue Bao 11(1) , 54-6, (1990)

Using the improved Kirsner model of ulcerative colitis in rabbits, we found that the therapeutic effect of methyl 5-amino salicylate hydrochloride (M-5-AS) was similar to that of sulfasalazine (salicy...

[Teratologic studies of methyl 5-aminosalicylate and salicylazopyridine].

Zhongguo Yao Li Xue Bao 13(3) , 265-7, (1992)

Methyl 5-aminosalicylate hydrochloride (M-5-AS) at the dosages of 21, 42, 209, and 417 mg.kg-1.d-1 ig to mice during d 6-15 of pregnancy, no obvious effects on the placenta, fetus weight, sex differen...

Synonyms

Benzoic acid, 5-amino-2-hydroxy-, methyl ester

MFCD01317557

Benzoic acid, 5-amino-2-hydroxy-, methyl ester (9CI)

Methyl 5-amino-2-hydroxybenzoate

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