CAS 84-54-8|Tectoquinone
| Common Name | Tectoquinone | ||
|---|---|---|---|
| CAS Number | 84-54-8 | Molecular Weight | 222.239 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 407.8±35.0 °C at 760 mmHg |
| Molecular Formula | C15H10O2 | Melting Point | 170-173 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 152.7±22.9 °C |
Names
| Name | 2-methylanthraquinone |
|---|---|
| Synonym | More Synonyms |
Tectoquinone BiologicalActivity
| Description | Tectoquinone (2-Methylanthraquinone) is a SARSCoV-2 main protease inhibitor against COVID-19. Tectoquinone exhibits strong mosquito larvicidal activity with the LC50 values of 3.3 and 5.4 μg/ml against A. aegypti and A. albopictus in 24 h, respectively[1][2]. |
|---|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>SARS-CoV |
| References | [1]. Sen-Sung Cheng, et al. Larvicidal activity of tectoquinone isolated from red heartwood-type Cryptomeria japonica against two mosquito species. Bioresour Technol. 2008 Jun;99(9):3617-22. [2]. Anoop Kallingal, et al. Molecular modeling study of tectoquinone and acteoside from Tectona grandis linn: a new SARS-CoV-2 main protease inhibitor against COVID-19. J Biomol Struct Dyn. 2022 Mar;40(4):1764-1775. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 407.8±35.0 °C at 760 mmHg |
| Melting Point | 170-173 °C(lit.) |
| Molecular Formula | C15H10O2 |
| Molecular Weight | 222.239 |
| Flash Point | 152.7±22.9 °C |
| Exact Mass | 222.068085 |
| PSA | 34.14000 |
| LogP | 3.84 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.644 |
| InChIKey | NJWGQARXZDRHCD-UHFFFAOYSA-N |
| SMILES | Cc1ccc2c(c1)C(=O)c1ccccc1C2=O |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves |
|---|---|
| Hazard Codes | Xi,N |
| Risk Phrases | R51/53 |
| Safety Phrases | S22-S24/25-S61 |
| RIDADR | UN 3077 9/PG 3 |
| WGK Germany | 3 |
| Hazard Class | 5.2 |
| HS Code | 2914399090 |
Customs
| HS Code | 2914690090 |
|---|---|
| Summary | 2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
Articles8
More Articles| [Chemical constituents of Morinda officinalis How]. Zhongguo Zhong Yao Za Zhi 16(11) , 675-6, 703, (1991) This paper reports the identification of four compounds isolated from the cortex of Morinda officinalis growing in Guangdong Province. These compounds are beta-sitosterol (I), 2-methyl-anthraquinone(I... | |
| [Studies on the chemical constituents from stem of Chirita longgangensis var. Hongyao]. Zhongguo Zhong Yao Za Zhi 31(4) , 307-8, (2006) To isolate and elucidate the constituents from stem of Chirita longgangensis var. hongyao.The constituents were extracted with methanol and isolated by chromatography on silica gel, Sephadex LH-20 and... | |
| PPARγ agonist from Chromolaena odorata. J. Nat. Prod. 75(12) , 2076-81, (2012) A phytochemical investigation of Chromolaena odorata resulted in the isolation of five new compounds, 5aα,6,9,9aβ,10-pentahydro-10β-hydroxy-7-methylanthra[1,2-d][1,3]dioxol-5-one (1), 1,2-methylenedio... |
Synonyms
| 2-Methylanthraquinone |
| 9,10-Anthracenedione, 2-methyl- |
| 2-Methyl anthraquinone |
| EINECS 201-539-6 |
| MFCD00001235 |
| 2-Methyl-9,10-anthraquinone |
| 2-methylanthracene-9,10-dione |
