CAS 95-73-8|2,4-Dichlorotoluene

Introduction：Basic information about CAS 95-73-8|2,4-Dichlorotoluene, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles7
7. Synonyms

Common Name	2,4-Dichlorotoluene
CAS Number	95-73-8	Molecular Weight	161.029
Density	1.2±0.1 g/cm3	Boiling Point	198.6±20.0 °C at 760 mmHg
Molecular Formula	C₇H₆Cl₂	Melting Point	-14 °C
MSDS	ChineseUSA	Flash Point	79.4±0.0 °C

Names

Name	2,4-Dichlorotoluene
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	198.6±20.0 °C at 760 mmHg
Melting Point	-14 °C
Molecular Formula	C₇H₆Cl₂
Molecular Weight	161.029
Flash Point	79.4±0.0 °C
Exact Mass	159.984650
LogP	3.88
Vapour Pressure	0.5±0.4 mmHg at 25°C
Index of Refraction	1.543
InChIKey	FUNUTBJJKQIVSY-UHFFFAOYSA-N
SMILES	Cc1ccc(Cl)cc1Cl
Water Solubility	immiscible

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XT0730000

CHEMICAL NAME :: Toluene, 2,4-dichloro-

CAS REGISTRY NUMBER :: 95-73-8

BEILSTEIN REFERENCE NO. :: 1931691

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C7-H6-Cl2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2400 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - muscle weakness

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 25(10),56,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2400 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - muscle weakness

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 25(10),56,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 53(2),80,1988 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6440 mg/kg/2W-I

TOXIC EFFECTS :: Liver - other changes Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 52(11),86,1987

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 28980 mg/kg/9W-I

TOXIC EFFECTS :: Liver - fatty liver degeneration Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 53(2),80,1988

Safety Information

Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S23-S24/25
RIDADR	UN 2810
WGK Germany	2
RTECS	XT0730000
Packaging Group	III
Hazard Class	9
HS Code	29036990

Customs

HS Code	2903999090
Summary	2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles7

Metabolism of dichloromethylcatechols as central intermediates in the degradation of dichlorotoluenes by Ralstonia sp. strain PS12.

J. Bacteriol. 184(19) , 5261-74, (2002)

Ralstonia sp. strain PS12 is able to use 2,4-, 2,5-, and 3,4-dichlorotoluene as growth substrates. Dichloromethylcatechols are central intermediates that are formed by TecA tetrachlorobenzene dioxygen...

Development of a solid-phase microextraction-gas chromatography-tandem mass spectrometry method for the analysis of chlorinated toluenes in environmental waters.

J. Chromatogr. A. 1216(14) , 2816-24, (2009)

In the present work, a simple and fast methodology has been developed for the analysis of chlorotoluenes in water samples using solid-phase microextraction (SPME) coupled to gas chromatography-tandem ...

Rapid and selective catalytic oxidation of secondary alcohols at room temperature by using (N-heterocyclic carbene)-ni(0) systems.

Chemistry 16(23) , 6857-60, (2010)

The selective, anaerobic catalytic oxidation of secondary alcohols at room temperature by using an in situ (N-heterocyclic carbene)-Ni(0) system is presented. The use of non-anhydrous, non-degassed 2,...

Synonyms

2,4-Dichlorotoluene

2,4-Dichlor-toluol

2,4-dichloro-1-methyl-benzene

2,4-Dichloro-1-methylbenzene

EINECS 202-445-8

2,4-dichloro-toluene

Benzene, 2,4-dichloro-1-methyl-

4,6-dichlorothieno<2,3-b>pyridine

MFCD00000583

4,6-dichlorotoluene

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