CAS 596-03-2|4',5'-DIBROMOFLUORESCEIN

Introduction:Basic information about CAS 596-03-2|4',5'-DIBROMOFLUORESCEIN, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name4',5'-DIBROMOFLUORESCEIN
CAS Number596-03-2Molecular Weight490.09800
Density2.1 g/cm3Boiling Point633.7ºC at 760 mmHg
Molecular FormulaC20H10Br2O5Melting Point270-273 °C(lit.)
MSDSChineseUSAFlash Point337ºC
Symbol
GHS06
Signal WordDanger

Names

Name4',5'-Dibromofluorescein
SynonymMore Synonyms

4',5'-DIBROMOFLUORESCEIN BiologicalActivity

Description4',5'-Dibromofluorescein (Eosinic acid) is a fluorescein derivative that can used as a ligand for studying of protein properties by spectral analysis[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. Dongdong Yu, et al. An ultrasensitive stain for negative protein detection in SDS-PAGE via 4',5'-Dibromofluorescein. J Proteomics. 2017 Aug 8;165:21-25.

Chemical & Physical Properties

Density2.1 g/cm3
Boiling Point633.7ºC at 760 mmHg
Melting Point270-273 °C(lit.)
Molecular FormulaC20H10Br2O5
Molecular Weight490.09800
Flash Point337ºC
Exact Mass487.88900
PSA75.99000
LogP5.19080
Index of Refraction1.771
InChIKeyZDTNHRWWURISAA-UHFFFAOYSA-N
SMILESO=C1OC2(c3ccccc31)c1ccc(O)c(Br)c1Oc1c2ccc(O)c1Br

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LM5200000
CHEMICAL NAME :
Fluorescein, 4',5'-dibromo-
CAS REGISTRY NUMBER :
596-03-2
BEILSTEIN REFERENCE NO. :
0057189
LAST UPDATED :
199710
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C20-H10-Br2-O5
MOLECULAR WEIGHT :
490.12
WISWESSER LINE NOTATION :
T C666 BO EVJ DE IR BVQ& MQ NE

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
15556 mg/kg/21D-C
TOXIC EFFECTS :
Kidney, Ureter, Bladder - other changes in urine composition Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Related to Chronic Data - changes in ovarian weight

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
100 ng/plate
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 1,116,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T1904 No. of Facilities: 237 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 6161 (estimated) No. of Female Employees: 474 (estimated)

Safety Information

Symbol
GHS06
Signal WordDanger
Hazard StatementsH301
Precautionary StatementsP301 + P310
Personal Protective EquipmentEyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard CodesXi: Irritant;
Risk PhrasesR36
Safety PhrasesS22-S24/25-S45
RIDADRUN 2811 6.1/PG 3
WGK Germany3
RTECSLM5200000
HS Code2932999099

Customs

HS Code2932999099
Summary2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

MFCD00005042
EINECS 209-876-0
4',5'-dibromo-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
CAS 6994-46-3|solvent
CAS 1147-56-4|NSC139021
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