Introduction:Basic information about CAS 596-03-2|4',5'-DIBROMOFLUORESCEIN, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4',5'-DIBROMOFLUORESCEIN |
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| CAS Number | 596-03-2 | Molecular Weight | 490.09800 |
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| Density | 2.1 g/cm3 | Boiling Point | 633.7ºC at 760 mmHg |
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| Molecular Formula | C20H10Br2O5 | Melting Point | 270-273 °C(lit.) |
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| MSDS | ChineseUSA | Flash Point | 337ºC |
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| Symbol | GHS06 | Signal Word | Danger |
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Names
| Name | 4',5'-Dibromofluorescein |
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| Synonym | More Synonyms |
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4',5'-DIBROMOFLUORESCEIN BiologicalActivity
| Description | 4',5'-Dibromofluorescein (Eosinic acid) is a fluorescein derivative that can used as a ligand for studying of protein properties by spectral analysis[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. Dongdong Yu, et al. An ultrasensitive stain for negative protein detection in SDS-PAGE via 4',5'-Dibromofluorescein. J Proteomics. 2017 Aug 8;165:21-25. |
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Chemical & Physical Properties
| Density | 2.1 g/cm3 |
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| Boiling Point | 633.7ºC at 760 mmHg |
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| Melting Point | 270-273 °C(lit.) |
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| Molecular Formula | C20H10Br2O5 |
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| Molecular Weight | 490.09800 |
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| Flash Point | 337ºC |
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| Exact Mass | 487.88900 |
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| PSA | 75.99000 |
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| LogP | 5.19080 |
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| Index of Refraction | 1.771 |
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| InChIKey | ZDTNHRWWURISAA-UHFFFAOYSA-N |
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| SMILES | O=C1OC2(c3ccccc31)c1ccc(O)c(Br)c1Oc1c2ccc(O)c1Br |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- LM5200000
- CHEMICAL NAME :
- Fluorescein, 4',5'-dibromo-
- CAS REGISTRY NUMBER :
- 596-03-2
- BEILSTEIN REFERENCE NO. :
- 0057189
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C20-H10-Br2-O5
- MOLECULAR WEIGHT :
- 490.12
- WISWESSER LINE NOTATION :
- T C666 BO EVJ DE IR BVQ& MQ NE
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 15556 mg/kg/21D-C
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes in urine composition Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Related to Chronic Data - changes in ovarian weight
MUTATION DATA - TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 100 ng/plate
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 1,116,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T1904 No. of Facilities: 237 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 6161 (estimated) No. of Female Employees: 474 (estimated)
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Safety Information
| Symbol | GHS06 |
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| Signal Word | Danger |
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| Hazard Statements | H301 |
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| Precautionary Statements | P301 + P310 |
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| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
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| Hazard Codes | Xi: Irritant; |
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| Risk Phrases | R36 |
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| Safety Phrases | S22-S24/25-S45 |
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| RIDADR | UN 2811 6.1/PG 3 |
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| WGK Germany | 3 |
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| RTECS | LM5200000 |
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| HS Code | 2932999099 |
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Customs
| HS Code | 2932999099 |
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| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| MFCD00005042 |
| EINECS 209-876-0 |
| 4',5'-dibromo-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one |