Introduction：Basic information about CAS 113919-36-1|2-(PHOSPHONOMETHYL)-PENTANEDIOIC ACID, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-(PHOSPHONOMETHYL)-PENTANEDIOIC ACID |
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| CAS Number | 113919-36-1 | Molecular Weight | 224.15200 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C6H13N2O5P | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 4-(phosphonomethyl)piperazine-2-carboxylic acid |
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2-(PHOSPHONOMETHYL)-PENTANEDIOIC ACID BiologicalActivity
| Description | PMPA (NMDA antagonist) is an NMDA receptor antagonist with Ki values of 0.84, 2.74, 3.53 and 4.16 μM for NR2A, NR2B, NR2C and NR2D, respectively[1]. |
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| Related Catalog | Signaling Pathways >>Neuronal Signaling >>iGluRResearch Areas >>Neurological DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>iGluR |
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| Target | Ki: 0.84 μM (NR2A), 2.74 μM (NR2B), 3.53 μM (NR2C), 4.16 μM (NR2D)[1] |
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| References | [1]. Feng B, et al. The effect of competitive antagonist chain length on NMDA receptor subunit selectivity. Neuropharmacology. 2005 Mar;48(3):354-9. |
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Chemical & Physical Properties
| Molecular Formula | C6H13N2O5P |
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| Molecular Weight | 224.15200 |
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| Exact Mass | 224.05600 |
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| PSA | 119.91000 |
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| InChIKey | ILRBBHJXTYIHTP-UHFFFAOYSA-N |
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| SMILES | O=C(O)C1CN(CP(=O)(O)O)CCN1 |
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