CAS 159439-02-8|Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH

Introduction：Basic information about CAS 159439-02-8|Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH
CAS Number	159439-02-8	Molecular Weight	803.705
Density	1.4±0.1 g/cm3	Boiling Point	/
Molecular Formula	C₃₂H₄₆N₅O₁₇P	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu,N-Acetyl-O-phosphono-L-tyrosyl-L-α-glutamyl-L-α-glutamyl]-L-α-glutamyl-L-isoleucyl]-L-glutamicacid
Synonym	More Synonyms

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH BiologicalActivity

Description	Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC50≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH is an inhibitor for src SH3-SH2:phosphoprotein interactions[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Protein Tyrosine Kinase/RTK >>Src
References	[1]. G J Pacofsky, et al. Potent dipeptide inhibitors of the pp60c-src SH2 domain. J Med Chem. 1998 May 21;41(11):1894-908.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Molecular Formula	C₃₂H₄₆N₅O₁₇P
Molecular Weight	803.705
Exact Mass	803.262634
PSA	371.27000
LogP	-2.73
Index of Refraction	1.573
InChIKey	QQEKQSBIEKQXQS-PSCZMIBCSA-N
SMILES	CCC(C)C(NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(Cc1ccc(OP(=O)(O)O)cc1)NC(C)=O)C(=O)NC(CCC(=O)O)C(=O)O

Synonyms

N-Acetyl-O-phosphono-L-tyrosyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl-L-glutamic acid

N-ACETYL-O-PHOSPHONO-TYR-GLU-GLU-ILE-GLU

N-Acetyl-O-phosphono-Tyr-Glu-Glu-Glu-Ile-Glu

AC-YEEIE

AC-PYEEIE TRIFLUOROACETATE SALT

N-ACETYL-O-PHOSPHONE-TYR-GLU*DIPENTYLAMI

M.W. 803.71 C32H46N5O17P

L-Glutamic acid, N-acetyl-O-phosphono-L-tyrosyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl-

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