CAS 197230-90-3|Acetyl-Neurotrophin Receptor (368-381) amide (human)

Introduction:Basic information about CAS 197230-90-3|Acetyl-Neurotrophin Receptor (368-381) amide (human), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameAcetyl-Neurotrophin Receptor (368-381) amide (human)
CAS Number197230-90-3Molecular Weight1565.86000
Density/Boiling Point/
Molecular FormulaC69H124N22O19Melting Point/
MSDS/Flash Point/

Names

Namentr 368
SynonymMore Synonyms

BiologicalActivity

DescriptionNTR 368 is a peptide derived from p75 neurotrophin receptor (p75NTR) corresponding to residues 368-381 of the human receptor. NTR 368 has helix forming propensity in the presence of micellar lipid. NTR 368 is a potent inducer of neural apoptosis[1].
Related CatalogSignaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Neurological Disease
References

[1]. M R Hileman, et al. A cytoplasmic peptide of the neurotrophin receptor p75NTR: induction of apoptosis and NMR determined helical conformation. FEBS Lett. 1997 Sep 29;415(2):145-54.

Chemical & Physical Properties

Molecular FormulaC69H124N22O19
Molecular Weight1565.86000
Exact Mass1564.94000
PSA674.91000
LogP3.49150
InChIKeyZUALDXYFESKMAR-SMVIZIMZSA-N
SMILESCCC(C)C(NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(C)NC(C)=O)C(C)O)C(=O)NC(CCC(N)=O)C(N)=O

Synonyms

m.w. 1565.86 c69h124n22o19
ac-ala-thr-leu-asp-ala-leu-leu-ala-ala-leu-arg-arg-ile-gln-nh2
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