Introduction：Basic information about CAS 85872-53-3|1,3-Dipropyl-8-phenylxanthine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 1,3-Dipropyl-8-phenylxanthine |
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| CAS Number | 85872-53-3 | Molecular Weight | 312.36600 |
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| Density | 1.218g/cm3 | Boiling Point | 539.1ºC at 760 mmHg |
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| Molecular Formula | C17H20N4O2 | Melting Point | / |
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| MSDS | / | Flash Point | 279.8ºC |
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Names
| Name | 1,3-Dipropyl-8-phenylxanthine |
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| Synonym | More Synonyms |
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1,3-Dipropyl-8-phenylxanthine BiologicalActivity
| Description | NPC 200 is a potent and selective antagonist of Adenosine A1 Receptor. NPC 200 reverses NECA-induced left and right atrial depression with EC50s of 1.08 and 2.03 μM[1]. |
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| Related Catalog | Research Areas >>Inflammation/ImmunologySignaling Pathways >>GPCR/G Protein >>Adenosine Receptor |
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| References | [1]. P. V. Kaplita, et al. NPC 205 is a potent and selective adenosine A1, receptor antagonist: Correlation among receptor binding, biochemical, and physiological assays. , 20(4), 429–443. |
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Chemical & Physical Properties
| Density | 1.218g/cm3 |
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| Boiling Point | 539.1ºC at 760 mmHg |
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| Molecular Formula | C17H20N4O2 |
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| Molecular Weight | 312.36600 |
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| Flash Point | 279.8ºC |
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| Exact Mass | 312.15900 |
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| PSA | 72.68000 |
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| LogP | 2.37330 |
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| Index of Refraction | 1.587 |
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| InChIKey | CLIGSMOZKDCDRZ-UHFFFAOYSA-N |
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| SMILES | CCCn1c(=O)c2[nH]c(-c3ccccc3)nc2n(CCC)c1=O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- UO8430880
- CHEMICAL NAME :
- 1H-Purine-2,6,dione, 3,7-dihydro-1,3-dipropyl-8-phenyl-
- CAS REGISTRY NUMBER :
- 85872-53-3
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #5032593
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Safety Information
Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| dione,3,7-dihydro-1,3-dipropyl-8-phenyl-1h-purine-6 |
| 3,9-Dihydro-8-phenyl-1,3-dipropyl-1H-purine-2,6-dione |
| 1,3-dipropyl-8-phenyl xanthine |
| NPC-200 |
| 3,7-dihydro-1,3-dipropyl-8-phenyl-1h-purine-2,6,dione |
