Introduction：Basic information about CAS 19367-38-5|Methyl (2Z)-3-(4-hydroxyphenyl)acrylate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Methyl (2Z)-3-(4-hydroxyphenyl)acrylate |
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| CAS Number | 19367-38-5 | Molecular Weight | 178.185 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 306.6±17.0 °C at 760 mmHg |
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| Molecular Formula | C10H10O3 | Melting Point | 138-140ºC |
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| MSDS | / | Flash Point | 132.8±13.7 °C |
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Names
| Name | Methyl 4-hydroxycinnamate |
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| Synonym | More Synonyms |
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Methyl (2Z)-3-(4-hydroxyphenyl)acrylate BiologicalActivity
| Description | (E)-Methyl 4-coumarate (Methyl 4-hydroxycinnamate), found in several plants, such as green onion (Allium cepa) or noni (Morinda citrifolia L.) leaves. (E)-Methyl 4-coumarate cooperates with Carnosic Acid in inducing apoptosis and killing acute myeloid leukemia cells, but not normal peripheral blood mononuclear cells. Antioxidant and antimicrobial activity. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>CancerResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| References | [1]. Trachtenberg A, et al. Synergistic Cytotoxicity of Methyl 4-Hydroxycinnamate and Carnosic Acid to Acute Myeloid Leukemia Cells via Calcium-Dependent Apoptosis Induction. Front Pharmacol. 2019 May 9;10:507. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 306.6±17.0 °C at 760 mmHg |
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| Melting Point | 138-140ºC |
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| Molecular Formula | C10H10O3 |
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| Molecular Weight | 178.185 |
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| Flash Point | 132.8±13.7 °C |
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| Exact Mass | 178.062988 |
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| PSA | 46.53000 |
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| LogP | 1.64 |
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| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
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| Index of Refraction | 1.593 |
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| InChIKey | NITWSHWHQAQBAW-QPJJXVBHSA-N |
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| SMILES | COC(=O)C=Cc1ccc(O)cc1 |
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| Storage condition | Refrigerator |
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Safety Information
| Hazard Codes | Xi: Irritant; |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S26-S36/37/39 |
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Synonyms
| 4-Hydroxy MethylesterCinnaMatc |
| METHYL 4-COUMARATE |
| 4-hydroxycinnamic acid methyl ester |
| Methyl trans-p-Coumarate |
| METHYL P-HYDROXYCINNAMATE |
| Methyl (2Z)-3-(4-hydroxyphenyl)acrylate |
| Methyl trans-4-Hydroxycinnamate |
| Methyl 4-hydroxyphenylacrylate |
| METHYL COUMARATE |
| METHYL 3-HYDROXYCINNAMATE |
| trans-4-Hydroxycinnamic Acid Methyl Ester |
| (E)-Methyl 3-(4-hydroxyphenyl)acrylate |
| 4-hydroxyphenyl-acrylic acid methyl ester |
| 2-Propenoic acid, 3-(4-hydroxyphenyl)-, methyl ester, (2Z)- |
| Methyl trans-p-hydroxycinnaMate |
| MFCD00157167 |
| trans-p-Coumaric Acid Methyl Ester |
