Introduction：Basic information about CAS 86770-67-4|Azido-PEG4-alcohol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Azido-PEG4-alcohol |
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| CAS Number | 86770-67-4 | Molecular Weight | 219.23800 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C8H17N3O4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethanol |
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| Synonym | More Synonyms |
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Azido-PEG4-alcohol BiologicalActivity
| Description | Azido-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228. |
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Chemical & Physical Properties
| Molecular Formula | C8H17N3O4 |
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| Molecular Weight | 219.23800 |
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| Exact Mass | 219.12200 |
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| PSA | 97.67000 |
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| Index of Refraction | 1.47 |
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| InChIKey | MBQYGQMGPFNSAP-UHFFFAOYSA-N |
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| SMILES | [N-]=[N+]=NCCOCCOCCOCCO |
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Synonyms
| 1-AZIDO-3,6,9-TRIOXAUNDECANE-11-OL |
| Azido-PEG4-alcohol |
| 1-azido-3,6,9-trioxaundecan-11-ol |
| 1-azido-11-hydroxy-3,6,9-trioxaundecane |
