Introduction：Basic information about CAS 68489-09-8|WS 12, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | WS 12 |
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| CAS Number | 68489-09-8 | Molecular Weight | 289.41200 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C18H27NO2 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | (1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-propan-2-ylcyclohexane-1-carboxamide |
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| Synonym | More Synonyms |
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WS 12 BiologicalActivity
| Description | WS-12 is an agonist of TRPM8 with an EC50 of 39 nM. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>TRP ChannelResearch Areas >>Metabolic DiseaseResearch Areas >>Cancer |
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| Target | EC50: 39 nM (TRPM8)[1] |
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| References | [1]. Beck B, et al. Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators. Cell Calcium. 2007 Mar;41(3):285-94. |
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Chemical & Physical Properties
| Molecular Formula | C18H27NO2 |
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| Molecular Weight | 289.41200 |
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| Exact Mass | 289.20400 |
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| PSA | 38.33000 |
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| LogP | 4.41510 |
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| InChIKey | HNSGVPAAXJJOPQ-XOKHGSTOSA-N |
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| SMILES | COc1ccc(NC(=O)C2CC(C)CCC2C(C)C)cc1 |
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| Storage condition | 2-8℃ |
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Synonyms
| WS 12 |
| 7-Hydroxy-DPAT hydrobromide |
| WS-12 |
