CAS 151533-22-1|Levomefolate calcium

Introduction：Basic information about CAS 151533-22-1|Levomefolate calcium, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Levomefolate calcium BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Levomefolate calcium
CAS Number	151533-22-1	Molecular Weight	497.518
Density	/	Boiling Point	/
Molecular Formula	C₂₀H₂₃CaN₇O₆	Melting Point	>300ºC
MSDS	/	Flash Point	/

Names

Name	Levomefolate calcium
Synonym	More Synonyms

Levomefolate calcium BiologicalActivity

Description	Levomefolate is an artificial form of folate.IC50 Value:Target: AntifolateThe calcium salt of L-5-methyltetrahydrofolic acid which belongs to the group of folate vitamins (Vitamin B9, Folacin). It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.
Related Catalog	Signaling Pathways >>Cell Cycle/DNA Damage >>AntifolateResearch Areas >>Cancer
References	[1]. Fruzzetti F. Beyaz®: an oral contraceptive fortified with folate. Womens Health (Lond Engl). 2012 Jan;8(1):13-9. [2]. Wiesinger H, Eydeler U, Richard F, et al. Bioequivalence evaluation of a folate-supplemented oral contraceptive containing ethinylestradiol/drospirenone/levomefolate calcium versus ethinylestradiol/drospirenone and levomefolate calcium alone. Clin Drug Investig. 2012 Oct 1;32(10):673-84. [3]. Hartmut Blodea, Christine Klippingb, Frank Richardc, et al. Bioequivalence study of an oral contraceptive containing ethinylestradiol/drospirenone/levomefolate calcium relative to ethinylestradiol/drospirenone and to levomefolate calcium alone. Contraception.2012, 85(2), :177-184 [4]. Rapkin RB, Creinin MD. The combined oral contraceptive pill containing drospirenone and ethinyl estradiol plus levomefolate calcium. Expert Opin Pharmacother. 2011 Oct;12(15):2403-10. doi: 10.1517/14656566.2011.610791. [5]. Levomefolic_acid

Description

Levomefolate is an artificial form of folate.IC50 Value:Target: AntifolateThe calcium salt of L-5-methyltetrahydrofolic acid which belongs to the group of folate vitamins (Vitamin B9, Folacin). It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.

Related Catalog

Signaling Pathways >>Cell Cycle/DNA Damage >>AntifolateResearch Areas >>Cancer

References

[1]. Fruzzetti F. Beyaz®: an oral contraceptive fortified with folate. Womens Health (Lond Engl). 2012 Jan;8(1):13-9.

[2]. Wiesinger H, Eydeler U, Richard F, et al. Bioequivalence evaluation of a folate-supplemented oral contraceptive containing ethinylestradiol/drospirenone/levomefolate calcium versus ethinylestradiol/drospirenone and levomefolate calcium alone. Clin Drug Investig. 2012 Oct 1;32(10):673-84.

[3]. Hartmut Blodea, Christine Klippingb, Frank Richardc, et al. Bioequivalence study of an oral contraceptive containing ethinylestradiol/drospirenone/levomefolate calcium relative to ethinylestradiol/drospirenone and to levomefolate calcium alone. Contraception.2012, 85(2), :177-184

[4]. Rapkin RB, Creinin MD. The combined oral contraceptive pill containing drospirenone and ethinyl estradiol plus levomefolate calcium. Expert Opin Pharmacother. 2011 Oct;12(15):2403-10. doi: 10.1517/14656566.2011.610791.

[5]. Levomefolic_acid

Chemical & Physical Properties

Melting Point	>300ºC
Molecular Formula	C₂₀H₂₃CaN₇O₆
Molecular Weight	497.518
Exact Mass	497.133575
PSA	208.43000
InChIKey	VWBBRFHSPXRJQD-QNTKWALQSA-L
SMILES	CN1c2c([O-])nc(N)nc2NCC1CNc1ccc(C(=O)NC(CCC(=O)[O-])C(=O)O)cc1.[Ca+2]
Storage condition	-20?C Freezer

Safety Information

Safety Phrases	24/25
HS Code	29339900

Synonyms

Bodyfolin

CALCIUML-5-METHYLTETRAHYDROFOLATE

Levomefolinate calcium

Nutrifolin

Calcium (2S)-2-{[4-({[(6S)-2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl]methyl}amino)benzoyl]amino}pentanedioate

L-5-MTHF-Ca

L-5-Methyltetrahydrofolate calcium

Levomefolate Calcium

L-5-Methyletrahydrofolate calciuM

Calcium levomefolate

L-Glutamic acid, N-[4-[[[(6S)-2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-, calcium salt (1:1)

LMCA

Calcium (2S)-2-{[4-({[(6S)-2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]amino}pentanedioate

Folic Acid Impurity 3

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