CAS 5926-26-1|(Chloromethyl)(trimethoxy)silane

Introduction：Basic information about CAS 5926-26-1|(Chloromethyl)(trimethoxy)silane, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Articles3
6. Synonyms

Common Name	(Chloromethyl)(trimethoxy)silane
CAS Number	5926-26-1	Molecular Weight	170.667
Density	1.1±0.1 g/cm3	Boiling Point	132.2±13.0 °C at 760 mmHg
Molecular Formula	C₄H₁₁ClO₃Si	Melting Point	/
MSDS	ChineseUSA	Flash Point	30.1±12.0 °C
Symbol	GHS02	Signal Word	Danger

Names

Name	(Chloromethyl)trimethoxysilane
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	132.2±13.0 °C at 760 mmHg
Molecular Formula	C₄H₁₁ClO₃Si
Molecular Weight	170.667
Flash Point	30.1±12.0 °C
Exact Mass	170.016602
PSA	27.69000
LogP	0.37
Vapour Pressure	11.0±0.2 mmHg at 25°C
Index of Refraction	1.405
InChIKey	FPOSCXQHGOVVPD-UHFFFAOYSA-N
SMILES	CO[Si](CCl)(OC)OC

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VV2625000

CHEMICAL NAME :: Silane, chloromethyl-trimethoxy-

CAS REGISTRY NUMBER :: 5926-26-1

LAST UPDATED :: 199806

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C4-H11-Cl-O3-Si

MOLECULAR WEIGHT :: 170.69

WISWESSER LINE NOTATION :: G1-SI-O1&O1&O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1222,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1222,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1222,1986

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3600 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1222,1986

Safety Information

Symbol	GHS02
Signal Word	Danger
Hazard Statements	H225
Precautionary Statements	P210
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	F
Risk Phrases	11
Safety Phrases	S16-S29-S33
RIDADR	UN 1993 3/PG 2
WGK Germany	3
Packaging Group	II

Articles3

Mesoporous Silica Nanoparticles with pH-Sensitive Nanovalves for Delivery of Moxifloxacin Provide Improved Treatment of Lethal Pneumonic Tularemia.

ACS Nano 9 , 10778-89, (2015)

We have optimized mesoporous silica nanoparticles (MSNs) functionalized with pH-sensitive nanovalves for the delivery of the broad spectrum fluoroquinolone moxifloxacin (MXF) and demonstrated its effi...

Autonomous in vitro anticancer drug release from mesoporous silica nanoparticles by pH-sensitive nanovalves.

J. Am. Chem. Soc. 132(36) , 12690-7, (2010)

Mesoporous silica nanoparticles (MSNP) have proven to be an extremely effective solid support for controlled drug delivery on account of the fact that their surfaces can be easily functionalized in or...

Space-confined click reactions in hierarchically organized silica monoliths. Keppeler M and Hüsing N

New J. Chem. 35(3) , 681-690, (2011)

Synonyms

G1-SI-O1&O1&O1

Chloromethyltrimethoxysilane

Silane, (chloromethyl)trimethoxy-

(Chloromethyl)(trimethoxy)silane

MFCD00468107

chloromethyl(trimethoxy)silane

Chloromethyl Trimethoxysilane

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