Introduction：Basic information about CAS 2668-66-8|Medrysone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Medrysone |
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| CAS Number | 2668-66-8 | Molecular Weight | 344.48800 |
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| Density | 1.13g/cm3 | Boiling Point | 492.3ºC at 760mmHg |
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| Molecular Formula | C22H32O3 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | 265.7ºC |
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Names
| Name | 6α-Methyl-11β-hydroxyprogesterone |
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| Synonym | More Synonyms |
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Medrysone BiologicalActivity
| Description | Medrysone is a corticosteroid, in ophthalmology for the treatment of eye inflammations. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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Chemical & Physical Properties
| Density | 1.13g/cm3 |
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| Boiling Point | 492.3ºC at 760mmHg |
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| Molecular Formula | C22H32O3 |
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| Molecular Weight | 344.48800 |
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| Flash Point | 265.7ºC |
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| Exact Mass | 344.23500 |
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| PSA | 54.37000 |
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| LogP | 3.94030 |
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| Vapour Pressure | 9.3E-12mmHg at 25°C |
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| Index of Refraction | 1.552 |
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| InChIKey | GZENKSODFLBBHQ-ILSZZQPISA-N |
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| SMILES | CC(=O)C1CCC2C3CC(C)C4=CC(=O)CCC4(C)C3C(O)CC12C |
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| Storage condition | 2-8℃ |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- TU5250000
- CHEMICAL NAME :
- Pregn-4-ene-3,20-dione, 11-beta-hydroxy-6-alpha-methyl-
- CAS REGISTRY NUMBER :
- 2668-66-8
- LAST UPDATED :
- 199504
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C22-H32-O3
- MOLECULAR WEIGHT :
- 344.54
- WISWESSER LINE NOTATION :
- L E5 B666 OV MUTJ A1 CQ E1 FV1 L1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 338 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,185,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3713 No. of Facilities: 10 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 711 (estimated) No. of Female Employees: 328 (estimated)
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| RTECS | TU5250000 |
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Articles11
More Articles
| Ocular pemphigus. J. Egypt. Med. Assoc. 61(7-8) , 511-22, (1978)
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| Efficacy of medrysone as anti-inflammatory agent. Indian J. Ophthalmol. 33(5) , 295-7, (1985)
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| Management of vernal conjunctivitis with steroid induced glaucoma--a comparative study. Indian J. Ophthalmol. 35(5-6) , 298-301, (1987)
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Synonyms
