Introduction：Basic information about CAS 150849-52-8|WST-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | WST-1 |
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| CAS Number | 150849-52-8 | Molecular Weight | 651.34400 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C19H11IN5NaO8S2 | Melting Point | > 300°C (dec.) |
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| MSDS | / | Flash Point | / |
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Names
| Name | sodium,4-[2-(4-iodophenyl)-3-(4-nitrophenyl)tetrazol-2-ium-5-yl]benzene-1,3-disulfonate |
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| Synonym | More Synonyms |
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WST-1 BiologicalActivity
| Description | WST-1 is a Tetrazolium dye, widely used in the cell viability assays. WST-1 produces a water-soluble formazan product (WST-1 formazan) that occurs at the cell surface in NADPH dependent manner in viable cells[1][2]. |
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| Related Catalog | Signaling Pathways >>Others >>Others |
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| In Vitro | WST-1 is used for a wide range of assays that include cell viability, proliferation, plasma membrane electron transport system, superoxide generation, superoxide dismutase, and xanthine oxidase assay[1]. A water-soluble formazan dye is produced from the reduction of WST-1 tetrazolium, of which optical density at 450 nm is measured to evaluate cell viability[1]. |
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| References | [1]. Kyung-Mi Joo, et al. Development and validation of UPLC method for WST-1 cell viability assay and its application to MCTT HCE™ eye irritation test for colorful substances. Toxicol In Vitro. 2019 Oct;60:412-419. [2]. Munetaka ISHIYAMA, et al. A new sulfonated tetrazolium salt that produces a highly water-soluble formazan dye. Chem. Pharm. Bull. 1993, 41(6): 1118-1122. |
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Chemical & Physical Properties
| Melting Point | > 300°C (dec.) |
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| Molecular Formula | C19H11IN5NaO8S2 |
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| Molecular Weight | 651.34400 |
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| Exact Mass | 650.89900 |
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| PSA | 211.57000 |
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| LogP | 4.21680 |
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| InChIKey | JUJBNYBVVQSIOU-UHFFFAOYSA-M |
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| SMILES | O=[N+]([O-])c1ccc(-[n+]2nc(-c3ccc(S(=O)(=O)[O-])cc3S(=O)(=O)[O-])nn2-c2ccc(I)cc2)cc1.[Na+] |
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| Storage condition | -20°C |
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Safety Information
Synonyms
