CAS 70217-82-2|Coelenterazine 400 a

Introduction:Basic information about CAS 70217-82-2|Coelenterazine 400 a, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameCoelenterazine 400 a
CAS Number70217-82-2Molecular Weight391.464
Density1.2±0.1 g/cm3Boiling Point551.4±60.0 °C at 760 mmHg
Molecular FormulaC26H21N3OMelting Point/
MSDS/Flash Point287.3±32.9 °C

Names

Name2,8-dibenzyl-6-phenyl-7H-imidazo[1,2-a]pyrazin-3-one
SynonymMore Synonyms

Coelenterazine 400 a BiologicalActivity

DescriptionCoelenteramine 400a (Bisdeoxycoelenterazine), a derivative of Coelenterazine, is a Renilla luciferase (RLuc) substrate. In the presence of Coelenteramine 400a, RLuc can emit blue light at 395 nm[1][2].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. Levi J, et, al. Bisdeoxycoelenterazine derivatives for improvement of bioluminescence resonance energy transfer assays. J Am Chem Soc. 2007 Oct 3;129(39):11900-1.

[2]. Bertrand L, et, al. The BRET2/arrestin assay in stable recombinant cells: a platform to screen for compounds that interact with G protein-coupled receptors (GPCRS). J Recept Signal Transduct Res. Feb-Nov 2002;22(1-4):533-41.

Chemical & Physical Properties

Density1.2±0.1 g/cm3
Boiling Point551.4±60.0 °C at 760 mmHg
Molecular FormulaC26H21N3O
Molecular Weight391.464
Flash Point287.3±32.9 °C
Exact Mass391.168457
PSA50.16000
LogP4.84
Vapour Pressure0.0±1.5 mmHg at 25°C
Index of Refraction1.662

Synonyms

BlueSyn C
DI-DEHYDRO COELENTERAZINE
Imidazo[1,2-a]pyrazin-3(7H)-one, 6-phenyl-2,8-bis(phenylmethyl)-
2,8-Dibenzyl-6-phenylimidazo[1,2-a]pyrazin-3(7H)-one
Coelenterazine 400 a
BISDEOXYCOELENTERAZINE
C-7010
coelenterazine-hh
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