CAS 1490-04-6|Menthol

Introduction：Basic information about CAS 1490-04-6|Menthol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Menthol BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
5. Safety Information
6. Articles54
7. Synonyms

Common Name	Menthol
CAS Number	1490-04-6	Molecular Weight	156.265
Density	0.9±0.1 g/cm3	Boiling Point	215.4±8.0 °C at 760 mmHg
Molecular Formula	C₁₀H₂₀O	Melting Point	34-36 â„ƒ(lit.)
MSDS	ChineseUSA	Flash Point	93.3±0.0 °C
Symbol	GHS05, GHS07	Signal Word	Danger

Names

Name	2-Isopropyl-5-methylcyclohexanol
Synonym	More Synonyms

Menthol BiologicalActivity

Description	Menthol is a natural analgesic compound. Menthol could cause a feeling of coolness due to stimulation of ‘cold’ receptors by inhibiting Ca++ currents of neuronal membranes[1].
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease
References	[1]. NicolettaGaleotti, et al. Menthol: a natural analgesic compound. Neuroscience Letters. 2002 Apr.

Chemical & Physical Properties

Density	0.9±0.1 g/cm3
Boiling Point	215.4±8.0 °C at 760 mmHg
Melting Point	34-36 â„ƒ(lit.)
Molecular Formula	C₁₀H₂₀O
Molecular Weight	156.265
Flash Point	93.3±0.0 °C
Exact Mass	156.151413
PSA	20.23000
LogP	3.20
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.457
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GW0554000

CHEMICAL NAME :: Cyclohexanol, 5-methyl-2-(1-methylethyl)-

CAS REGISTRY NUMBER :: 1490-04-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C10-H20-O

Safety Information

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H315-H318-H335
Precautionary Statements	P280-P305 + P351 + P338 + P310
Hazard Codes	Xn,Xi
Risk Phrases	37/38-41-48/20/22-40-22
Safety Phrases	36/37/39-36-26
RIDADR	UN 1888 6.1/PG 3
WGK Germany	2
RTECS	OT0525000

Articles54

Carbopol 934, 940 and Ultrez 10 as viscosity modifiers of palm olein esters based nano-scaled emulsion containing ibuprofen.

Pak. J. Pharm. Sci. 26(1) , 75-83, (2013)

Micro-emulsions and sometimes nano-emulsions are well known candidates to deliver drugs locally. However, the poor rheological properties are marginally affecting their acceptance pharmaceutically. Th...

Activation of human 5-hydroxytryptamine type 3 receptors via an allosteric transmembrane site.

Mol. Pharmacol. 87(1) , 87-95, (2015)

In common with other members of the Cys-loop family of pentameric ligand-gated ion channels, 5-hydroxytryptamine type 3 receptors (5-HT3Rs) are activated by the binding of a neurotransmitter to an ext...

Corneal sensory nerve activity in an experimental model of UV keratitis.

Invest. Ophthalmol. Vis. Sci. 55(6) , 3403-12, (2014)

To produce in guinea pigs a UV-induced keratitis, to analyze the effects of this pathology on corneal nerve activity.In anesthetized animals, one eye was exposed to 254 nm UV-C radiation (500-1000 mJ/...

Synonyms

(1R,2S,5R)-(−)-Menthol

levo-menthol

EINECS 216-074-4

(-)-(1R,3R,4S)-Menthol

(−)-menthol

(-)-trans-p-Methan-cis-3-ol

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol

Levomenthol

L-Menthol

(-)-(1R,2S,5R)-Menthol

(-)-MENTHYL ALCOHOL

(1R)-(-)-Menthol

(R)-(-)-Menthol

DL-Menthol

(1R,2S,5R)-5-methyl-2-propan-2-yl-cyclohexan-1-ol

[1R-(1a,2b,5a)]-5-Methyl-2-(1-methylethyl)cyclohexanol

(-)-p-Menthan-3-ol

Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1R,2S,5R)-

(-)-Menthol

UNII:YS08XHA860

Menthol, l-

Menthol

(1R,2S,5R)-(-)-Menthol

MFCD00001484

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