Introduction：Basic information about CAS 150436-68-3|sodium 2-(4-methoxyphenoxy) propionate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | sodium 2-(4-methoxyphenoxy) propionate |
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| CAS Number | 150436-68-3 | Molecular Weight | 196.200 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 331.6±17.0 °C at 760 mmHg |
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| Molecular Formula | C10H12O4 | Melting Point | / |
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| MSDS | / | Flash Point | 130.3±14.4 °C |
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Names
| Name | (+/-)-2-(p-methoxyphenoxy)propionic acid |
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| Synonym | More Synonyms |
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sodium 2-(4-methoxyphenoxy) propionate BiologicalActivity
| Description | Lactisole is a canonical antagonist of sweet taste receptor, selectively targeting to T1R3 subunit, a glucose-sensing receptor. Lactisole inhibits insulin secretion induced by glucose in mouse islets[1][2]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
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| Target | T1R3[1] |
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| In Vitro | Lactisole (3-10 mM; 48 h) 在小鼠胰腺 β 细胞 MIN6 中抑制 Acesulfame-K、Sucralose (HY-N0614) 和 Glycyrrhizin (HY-N0184) 诱导的胰岛素分泌 (IC50~4 mM)[1]。 Lactisole (5 mM; 48 h) 可减弱由 Sucralos 和 Acesulfame-K 引起的细胞质 Ca2+ 浓度升高 ([Ca2+]c)，而不影响细胞内 cAMP 浓度升高 ([cAMP]c)[1]。 |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 331.6±17.0 °C at 760 mmHg |
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| Molecular Formula | C10H12O4 |
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| Molecular Weight | 196.200 |
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| Flash Point | 130.3±14.4 °C |
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| Exact Mass | 196.073563 |
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| PSA | 55.76000 |
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| LogP | 1.65 |
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| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
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| Index of Refraction | 1.521 |
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Safety Information
| Hazard Codes | Xi |
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| Risk Phrases | 36/37/38 |
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| Safety Phrases | 26-36 |
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Synonyms
| 2-(4-Methoxyphenoxy)propanoic acid |
| PMP |
| (±)-2-(p-Methoxyphenoxy)propionic acid |
| UNII:K573UZ6O8U |
| Propanoic acid, 2-(4-methoxyphenoxy)- |
| 2-(4-Methoxyphenoxy)propionic acid |
