CAS 155569-91-8|Emamectin Benzoate

Introduction：Basic information about CAS 155569-91-8|Emamectin Benzoate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Emamectin Benzoate BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Synonyms

Common Name	Emamectin Benzoate
CAS Number	155569-91-8	Molecular Weight	1880.33
Density	/	Boiling Point	/
Molecular Formula	C₁₀₄H₁₅₄N₂O₂₈	Melting Point	141-146ºC
MSDS	/	Flash Point	/

Names

Name	Emamectin benzoate
Synonym	More Synonyms

Emamectin Benzoate BiologicalActivity

Description	Emamectin Benzoate (MK-244) works as a chloride channel activator by binding gamma aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropods.
Related Catalog	Signaling Pathways >>Membrane Transporter/Ion Channel >>GABA ReceptorSignaling Pathways >>Neuronal Signaling >>GABA ReceptorResearch Areas >>Infection
Target	GABA Receptor
In Vitro	Emamectin Benzoate stimulates the release of GABA from the synapses between nerve cells and while additionally increasing GABA's affinity for its receptor on the post-junction membrane of muscle cells in insects and arthropods.
References	[1]. Cheng X, et al. Effect of Emamectin Benzoate on Root-Knot Nematodes and Tomato Yield. PLoS One. 2015 Oct 28;10(10):e0141235.

Chemical & Physical Properties

Melting Point	141-146ºC
Molecular Formula	C₁₀₄H₁₅₄N₂O₂₈
Molecular Weight	1880.33
PSA	206.57000
LogP	4.62840
InChIKey	GCKZANITAMOIAR-FIQFZZJVSA-N
SMILES	CCC(C)C1OC2(C=CC1C)CC1CC(CC=C(C)C(OC3CC(OC)C(OC4CC(OC)C(NC)C(C)O4)C(C)O3)C(C)C=CC=C3COC4C(O)C(C)=CC(C(=O)O1)C34O)O2.O=C(O)c1ccccc1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CL1203005

CHEMICAL NAME :: Avermectin b', 4''-deoxy-4''-(methylamino)-, (4''R)-, benzoate (salt)

CAS REGISTRY NUMBER :: 155569-91-8

LAST UPDATED :: 199712

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 105 mg/kg

SEX/DURATION :: female 6-21 day(s) after conception lactating female 21 day(s) post-birth

TOXIC EFFECTS :: Reproductive - Maternal Effects - other effects Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - behavioral

REFERENCE :: NETEEC Neurotoxicology and Teratology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.9- 1987- Volume(issue)/page/year: 19,315,1997

Safety Information

Hazard Codes	T,N,Xi
Risk Phrases	25-36-50-57-58-36/37/38-50/53-23-21
Safety Phrases	26-36-45-60-61-36/37
RIDADR	UN 2811 6.1/PG 3
RTECS	CL1203005

Synonyms

(2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-6'-[(1S)-1-methylpropyl]-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-3-O-methyl-4-O-[2,4,6-trideoxy-3-O-methyl-4-(methylammonio)-a-L-arabino-hexopyranosyl]-a-L-arabino-hexopyranoside benzoate

Emamectin Benzoate

(1'R,2S,4'S,5S,6R,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-6-[(2S)-2-Butanyl]-21',24'-dihydroxy-5,11',13',22'-tetramethyl-2'-oxo-5,6-dihydrospiro[pyran-2,6'-[3,7,19]trioxatetracyclo[15.6.1.1. 0]pentacosa[10,14,16,22]tetraen]-12'-yl 2,6-dideoxy-3-O-methyl-4-O-[2,4,6-trideoxy-3-O-methyl-4-(methylammonio)-α-L-arabino-hexopyranosyl]-α-L-arabino-hexopyranoside benzoate

Emamectin (Benzoate)

(4''R)-4''-Deoxy-4''-(methylamino)-avermectin B1 benzoate

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