CAS 26116-56-3|9(S)-Erythromycylamine

Introduction：Basic information about CAS 26116-56-3|9(S)-Erythromycylamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 9(S)-Erythromycylamine BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Synonyms

Common Name	9(S)-Erythromycylamine
CAS Number	26116-56-3	Molecular Weight	734.96
Density	1.19g/cm3	Boiling Point	810.3ºC at 760mmHg
Molecular Formula	C₃₇H₇₀N₂O₁₂	Melting Point	/
MSDS	/	Flash Point	443.8ºC

Names

Name	Erythromycylamine
Synonym	More Synonyms

9(S)-Erythromycylamine BiologicalActivity

Description	Erythromycylamine is a macrolide antibiotic. Erythromycylamine has antibacterial activity against most Gram-positive cocci and M. catarrhalis[1][2].
Related Catalog	Research Areas >>Infection
References	[1]. Naik S, et al. In vitro activities of several new macrolide antibiotics against Mycobacterium avium complex. Antimicrob Agents Chemother. 1989 Sep;33(9):1614-6. [2]. Fernandes CJ, et al. Multi-centre collaborative study for the in vitro evaluation of new macrolides dirithromycin and erythromycylamine. Australian Group for Antimicrobial Resistance (AGAR). Pathology. 1995 Jan;27(1):74-8.

Description

Erythromycylamine is a macrolide antibiotic. Erythromycylamine has antibacterial activity against most Gram-positive cocci and M. catarrhalis[1][2].

Related Catalog

Research Areas >>Infection

References

[1]. Naik S, et al. In vitro activities of several new macrolide antibiotics against Mycobacterium avium complex. Antimicrob Agents Chemother. 1989 Sep;33(9):1614-6.

[2]. Fernandes CJ, et al. Multi-centre collaborative study for the in vitro evaluation of new macrolides dirithromycin and erythromycylamine. Australian Group for Antimicrobial Resistance (AGAR). Pathology. 1995 Jan;27(1):74-8.

Chemical & Physical Properties

Density	1.19g/cm3
Boiling Point	810.3ºC at 760mmHg
Molecular Formula	C₃₇H₇₀N₂O₁₂
Molecular Weight	734.96
Flash Point	443.8ºC
Exact Mass	734.49300
PSA	202.86000
LogP	2.24410
Vapour Pressure	2.15E-30mmHg at 25°C
Index of Refraction	1.539
InChIKey	XCLJRCAJSCMIND-JCTYMORFSA-N
SMILES	CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC2OC(C)CC(N(C)C)C2O)C(C)(O)CC(C)C(N)C(C)C(O)C1(C)O
Storage condition	2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KF4590000

CHEMICAL NAME :: Erythromycin, 9-amino-9-deoxo-, stereoisomer

CAS REGISTRY NUMBER :: 26116-56-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C37-H70-N2-O12

MOLECULAR WEIGHT :: 735.09

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 13,83,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 120 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 13,83,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 57500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 13,83,1978

Safety Information

Hazard Codes	Xi,N
Risk Phrases	41-50/53
Safety Phrases	26-39-60-61

Synonyms

MFCD00872156

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