Introduction：Basic information about CAS 555-29-3|3-Hydroxy-alpha-methyl-DL-tyrosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 3-Hydroxy-alpha-methyl-DL-tyrosine |
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| CAS Number | 555-29-3 | Molecular Weight | 211.214 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 441.6±45.0 °C at 760 mmHg |
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| Molecular Formula | C10H13NO4 | Melting Point | / |
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| MSDS | / | Flash Point | 220.9±28.7 °C |
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Names
| Name | 2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 441.6±45.0 °C at 760 mmHg |
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| Molecular Formula | C10H13NO4 |
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| Molecular Weight | 211.214 |
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| Flash Point | 220.9±28.7 °C |
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| Exact Mass | 211.084457 |
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| PSA | 103.78000 |
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| LogP | 0.13 |
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| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
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| Index of Refraction | 1.635 |
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| Storage condition | −20°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- AY5940000
- CHEMICAL NAME :
- Alanine, 3-(3,4-dihydroxyphenyl)-2-methyl-, DL-
- CAS REGISTRY NUMBER :
- 555-29-3
- LAST UPDATED :
- 199403
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C10-H13-N-O4
- MOLECULAR WEIGHT :
- 211.24
- WISWESSER LINE NOTATION :
- QVXZ1&1R CQ DQ
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5710 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-348,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 430 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-348,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5370 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-348,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1317 mg/kg
- TOXIC EFFECTS :
- Liver - hepatitis (hepatocellular necrosis), diffuse Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,1318,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1760 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-348,1989
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Safety Information
| Hazard Codes | Xi |
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| Risk Phrases | 36 |
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| Safety Phrases | 26-36/37 |
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| WGK Germany | 3 |
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Synonyms
| a-Methyl-L-dopa |
| α-Methyl-L-dopa |
| Dopegyt |
| EINECS 209-088-7 |
| 3-(3,4-Dihydroxyphenyl)-2-methyl alanine |
| L-(-)-b-(3,4-Dihydroxyphenyl)-a-methylalanine |
| L-(-)-α-Methyl-β-(3,4-dihydroxyphenyl)alanine |
| L-(-)-a-Methyl-b-(3,4-dihydroxyphenyl)alanine |
| rac Alpha-Methyl DOPA |
| 2-Methyl-3-(3,4-dihydroxyphenyl)-DL-alanine |
| a-Methyl Dopa |
| (+)-α-Methyldopa |
| Mulfasin |
| UNII:33TD13T99R |
| α-Methyl dopa |
| 3-Hydroxy-α-methyltyrosine |
| Metholes |
| Tyrosine, 3-hydroxy-α-methyl- |
| L-(a-Md) |
| L-α-Methyldopa |
| (-)-α-Methyldopa |
| 3-Hydroxy-α-methyl-L-tyrosine |
| L-Tyrosine, 3-hydroxy-α-methyl- |
| Dopamet |
| (S)-(-)-a-Methyldopa |
| a-Methyl-b-(3,4-dihydroxyphenyl)-L-alanine |
| Bayer 1440L |
| MFCD00065917 |
| Methyl dopa |
| Aldomet |
| l-a-Methyldopa |
| (S)-a-Methyldopa |
| ALDORIL |
| Alanine, 3- (3,4-dihydroxyphenyl)-2-methyl-, L- |
| Methyldopa |
| L-a-Methyl-3,4-dihydroxyphenylalanine |
| (-)-Methyldopa |
| Elanpres |
