CAS 556-02-5|D-Thr-OH

Introduction:Basic information about CAS 556-02-5|D-Thr-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameD-Thr-OH
CAS Number556-02-5Molecular Weight181.189
Density1.3±0.1 g/cm3Boiling Point385.2±32.0 °C at 760 mmHg
Molecular FormulaC9H11NO3Melting Point310-314ºC
MSDSChineseUSAFlash Point186.7±25.1 °C
Symbol
GHS07
Signal WordWarning

Names

NameD-tyrosine
SynonymMore Synonyms

D-Thr-OH BiologicalActivity

DescriptionD-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth[1][2].
Related CatalogSignaling Pathways >>Metabolic Enzyme/Protease >>TyrosinaseResearch Areas >>Metabolic Disease
Target

Tyrosinase[1]

References

[1]. Jisu Park, et al. D-tyrosine Negatively Regulates Melanin Synthesis by Competitively Inhibiting Tyrosinase Activity. Pigment Cell Melanoma Res. 2018 May;31(3):374-383.

[2]. Cong Yu, et al. Inhibition of Biofilm Formation by D-tyrosine: Effect of Bacterial Type and D-tyrosine Concentration. Water Res. 2016 Apr 1;92:173-9.

Chemical & Physical Properties

Density1.3±0.1 g/cm3
Boiling Point385.2±32.0 °C at 760 mmHg
Melting Point310-314ºC
Molecular FormulaC9H11NO3
Molecular Weight181.189
Flash Point186.7±25.1 °C
Exact Mass181.073898
PSA83.55000
LogP0.38
Vapour Pressure0.0±0.9 mmHg at 25°C
Index of Refraction1.614
InChIKeyOUYCCCASQSFEME-MRVPVSSYSA-N
SMILESNC(Cc1ccc(O)cc1)C(=O)O

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH315-H319-H335
Precautionary StatementsP261-P305 + P351 + P338
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXn: Harmful;
Risk PhrasesR36/37/38
Safety PhrasesS24/25
RIDADRNONH for all modes of transport
WGK Germany3
HS Code2922509090

Customs

HS Code2922509090
Summary2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles1

More Articles
Carbonic anhydrase activators: Activation of the beta-carbonic anhydrase from the pathogenic yeast Candida glabrata with amines and amino acids.

Bioorg. Med. Chem. Lett. 20 , 1701-4, (2010)

The protein encoded by the NCE103 gene of Candida glabrata, a beta-carbonic anhydrase (CA, EC 4.2.1.1) designated as CgCA, was investigated for its activation with amines and amino acids. CgCA was wea...

Synonyms

L-tyrosine zwitterion
hydrogen L-tyrosinate
MFCD00063073
(2R)-2-amino-3-(4-hydroxyphenyl)propanoic acid
a-Amino-p-hydroxyhydrocinnamic Acid
L-Phenylalanine, 4-hydroxy-
D-p-Tyrosine
EINECS 209-112-6
d-Tyr
Tyrosine, d-
H-Tyr-OH
Tyrosine
(R)-Tyrosine
L-Tyr
H-D-Tyr-OH
Tyr
(S)-(-)-Tyrosine
(S)-a-Amino-4-hydroxybenzenepropanoic acid
Tyrosine, L-
b-(p-Hydroxyphenyl)alanine
hydrogen D-tyrosinate
Benzenepropanoic acid, α-amino-4-hydroxy-, (S)-
Tyrosinum [Latin]
(S)-a-amino-4-hydroxy-Benzenepropanoic acid
(S)-tyrosine
(S)-α-amino-4-hydroxy-Benzenepropanoic acid
DL-tyrosine
D-Thr-OH
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