Introduction：Basic information about CAS 305372-39-8|Biotin-PEG2-Mal, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Biotin-PEG2-Mal |
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| CAS Number | 305372-39-8 | Molecular Weight | 525.618 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 897.0±65.0 °C at 760 mmHg |
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| Molecular Formula | C23H35N5O7S | Melting Point | / |
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| MSDS | / | Flash Point | 496.3±34.3 °C |
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Names
| Name | N-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethyl]-5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide |
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| Synonym | More Synonyms |
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Biotin-PEG2-Mal BiologicalActivity
| Description | Biotin-PEG2-Mal is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 897.0±65.0 °C at 760 mmHg |
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| Molecular Formula | C23H35N5O7S |
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| Molecular Weight | 525.618 |
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| Flash Point | 496.3±34.3 °C |
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| Exact Mass | 525.225708 |
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| PSA | 190.94000 |
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| LogP | -1.76 |
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| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
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| Index of Refraction | 1.550 |
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| InChIKey | UDPCXVIKHFVPSZ-HOIFWPIMSA-N |
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| SMILES | O=C(CCCCC1SCC2NC(=O)NC21)NCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O |
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| Storage condition | -20 ℃ |
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Safety Information
Synonyms
| N-Biotinyl-N'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-diamine |
| 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[2-[2-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)- |
| B3174 |
| N-{2-[2-(2-{[3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoyl]amino}ethoxy)ethoxy]ethyl}-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide |
| Maleimide-PEG2-Biotin |
