CAS 908258-58-2|m-PEG10-CH2COOH

Introduction:Basic information about CAS 908258-58-2|m-PEG10-CH2COOH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namem-PEG10-CH2COOH
CAS Number908258-58-2Molecular Weight530.60400
Density1.122Boiling Point/
Molecular FormulaC23H46O13Melting Point/
MSDS/Flash Point/

Names

Name2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
SynonymMore Synonyms

m-PEG10-CH2COOH BiologicalActivity

Descriptionm-PEG10-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Chemical & Physical Properties

Density1.122
Molecular FormulaC23H46O13
Molecular Weight530.60400
Exact Mass530.29400
PSA138.83000
InChIKeyDNJQYLLQMMESPG-UHFFFAOYSA-N
SMILESCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC(=O)O

Synonyms

(2-{2-[2-(2-{2-[2-(2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}ethoxy)ethoxy]-ethoxy}ethoxy)acetic acid
3,6,9,12,15,18,21,24,27,30,33-UNDECAOXATETRATRIACONTANOIC ACID
CAS 905827-27-2|(5R)-5-[(1S)-1,2-Dihydroxyethyl]-3,4-dihydroxy-2(5H)-furanone-1 ,1-diphenylmethanami
CAS 909708-65-2|Liguzinediol
Recommended......
TOP