Introduction：Basic information about CAS 119644-22-3|5-Chloro-2',3'-dideoxy-3'-fluoro-uridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5-Chloro-2',3'-dideoxy-3'-fluoro-uridine |
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| CAS Number | 119644-22-3 | Molecular Weight | 264.64 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C9H10ClFN2O4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 5-chloro-1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
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| Synonym | More Synonyms |
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5-Chloro-2',3'-dideoxy-3'-fluoro-uridine BiologicalActivity
| Description | Raluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Molecular Formula | C9H10ClFN2O4 |
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| Molecular Weight | 264.64 |
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| Exact Mass | 264.031311 |
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| PSA | 84.32000 |
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| LogP | -0.75 |
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| Index of Refraction | 1.588 |
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| InChIKey | WKVDSZYIGHLONN-RRKCRQDMSA-N |
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| SMILES | O=c1[nH]c(=O)n(C2CC(F)C(CO)O2)cc1Cl |
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Synonyms
| Raluridine |
| Fddclurd |
| FddClU |
| Uridine, 5-chloro-2',3'-dideoxy-3'-fluoro- |
| 935U83 |
| FddCIU |
| 5-Chloro-2',3'-dideoxy-3'-fluorouridine |
| BW 935U83 |
| 2',3'-Dideoxy-3'-fluoro-5-chlorouridine |
| 5-CHLORO-2',3'-DIDEOXY-3'-FLUORO-URIDINE |
