CAS 129-77-1|Piperidolate (hydrochloride)

Introduction:Basic information about CAS 129-77-1|Piperidolate (hydrochloride), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NamePiperidolate (hydrochloride)
CAS Number129-77-1Molecular Weight359.89000
Density/Boiling Point431.9ºC at 760mmHg
Molecular FormulaC21H26ClNO2Melting Point/
MSDS/Flash Point136ºC

Names

Name(1-ethylpiperidin-3-yl) 2,2-diphenylacetate,hydrochloride
SynonymMore Synonyms

Piperidolate (hydrochloride) BiologicalActivity

DescriptionPiperidolate hydrochloride is an antimuscarinic, inhibits intestinal cramp induced by acetylcholine (rats and dogs).
Related CatalogSignaling Pathways >>GPCR/G Protein >>mAChRSignaling Pathways >>Neuronal Signaling >>mAChRResearch Areas >>Neurological Disease

Chemical & Physical Properties

Boiling Point431.9ºC at 760mmHg
Molecular FormulaC21H26ClNO2
Molecular Weight359.89000
Flash Point136ºC
Exact Mass359.16500
PSA29.54000
LogP4.58590
Vapour Pressure1.16E-07mmHg at 25°C
InChIKeyRBGWCEWDAHDPEH-UHFFFAOYSA-N
SMILESCCN1CCCC(OC(=O)C(c2ccccc2)c2ccccc2)C1.Cl
Storage condition2-8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AH2975000
CHEMICAL NAME :
Acetic acid, diphenyl-, 1-ethyl-3-piperidyl ester, hydrochloride
CAS REGISTRY NUMBER :
129-77-1
LAST UPDATED :
199603
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C21-H25-N-O2.Cl-H
MOLECULAR WEIGHT :
359.93
WISWESSER LINE NOTATION :
T6NTJ A2 COVYR&R &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
19 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,97,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1040 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
26 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 104,269,1952
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
35 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,97,1969

Safety Information

RIDADRNONH for all modes of transport
HS Code2933399090

Customs

HS Code2933399090
Summary2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

Edelel hydrochloride
Piperidolat-hydrochlorid
Crapinon
MFCD00057377
Piperidolate HCl
1-Ethyl-3-piperidyl diphenylacetate hydrochloride
EINECS 204-964-5
Piperidolate hydrochloride
Dactil
N-Ethyl-3-piperidyl diphenylacetate hydrochloride
Dactil hydrochloride
Piperidolate (hydrochloride)
CAS 932528-67-1|1-(2-(4-(4-Fluorophenyl)piperazin-1-yl)-2-oxoethyl)-4,6-dimethyl-2-oxo-1,2-dihydropy
CAS 932475-17-7|1-{2-[4-(2-Fluorophenyl)piperazin-1-yl]-2-oxoethyl}-4,6-dimethyl-2-oxo-1,2-dihydropy
Recommended......
TOP