CAS 70030-11-4|3-Hydroxyphenazepam

Introduction：Basic information about CAS 70030-11-4|3-Hydroxyphenazepam, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 3-Hydroxyphenazepam BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	3-Hydroxyphenazepam
CAS Number	70030-11-4	Molecular Weight	365.61
Density	1.7±0.1 g/cm3	Boiling Point	544.5±50.0 °C at 760 mmHg
Molecular Formula	C₁₅H₁₀BrClN₂O₂	Melting Point	/
MSDS	/	Flash Point	283.1±30.1 °C

Names

Name	7-bromo-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one
Synonym	More Synonyms

3-Hydroxyphenazepam BiologicalActivity

Description	3-Hydroxyphenazepam is an active metabolite of Cinazepam. Cinazepam is a GABAA receptor agonist. 3-Hydroxyphenazepam can inhibit synaptosomal transporter-mediated [3H]GABA uptake[1].
Related Catalog	Research Areas >>Neurological Disease
References	[1]. Borisova T, et, al. GABAA receptor agonist cinazepam and its active metabolite 3-hydroxyphenazepam act differently at the presynaptic site. Eur Neuropsychopharmacol. 2021 Apr;45:39-51.

Chemical & Physical Properties

Density	1.7±0.1 g/cm3
Boiling Point	544.5±50.0 °C at 760 mmHg
Molecular Formula	C₁₅H₁₀BrClN₂O₂
Molecular Weight	365.61
Flash Point	283.1±30.1 °C
Exact Mass	363.961395
PSA	65.18000
LogP	2.46
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.712
InChIKey	KRJKJUWAZOWXNV-UHFFFAOYSA-N
SMILES	O=C1Nc2ccc(Br)cc2C(c2ccccc2Cl)=NC1O

Synonyms

3-Hydroxyfenazepam

7-bromo-5-(2-chlorophenyl)-3-hydroxy-1,2-dihydro-3H-1,4-benzodiazepin-2-one

3-Oxyfenazepam

7-bromo-5-(2-chloro-phenyl)-3-hydroxy-1,3-dihydro-benzo[e][1,4]diazepin-2-one

7-Bromo-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one

3-Hydroxyphenazepam

2H-1,4-Benzodiazepin-2-one, 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-

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