Introduction：Basic information about CAS 14348-21-1|Cnidicin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Cnidicin |
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| CAS Number | 14348-21-1 | Molecular Weight | 354.396 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 519.0±50.0 °C at 760 mmHg |
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| Molecular Formula | C21H22O5 | Melting Point | / |
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| MSDS | / | Flash Point | 267.7±30.1 °C |
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Names
| Name | cnidicin |
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| Synonym | More Synonyms |
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Cnidicin BiologicalActivity
| Description | Cnidicin is a coumarin from the root of Angelica koreana, and inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| In Vitro | Cnidicin shows a significant inhibition upon the release of beta-hexosaminidase from the cultured RBL-2H3 cells in a dose dependent manner (IC50= 25 μM) and upon the nitric oxide production from the activated RAW264.7 cells (IC50=7.5 μM)[1]. |
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| References | [1]. Ryu SY, et al. Cnidicin, a coumarin, from the root of Angelica koreana, inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells. Planta Med. 2001 Mar;67(2):172-4. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 519.0±50.0 °C at 760 mmHg |
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| Molecular Formula | C21H22O5 |
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| Molecular Weight | 354.396 |
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| Flash Point | 267.7±30.1 °C |
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| Exact Mass | 354.146729 |
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| PSA | 61.81000 |
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| LogP | 6.07 |
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| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
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| Index of Refraction | 1.580 |
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| InChIKey | HJMDOAWWVCOEDW-UHFFFAOYSA-N |
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| SMILES | CC(C)=CCOc1c2ccoc2c(OCC=C(C)C)c2oc(=O)ccc12 |
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| Storage condition | 2-8℃ |
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Synonyms
| 7H-Furo[3,2-g][1]benzopyran-7-one, 4,9-bis[(3-methyl-2-buten-1-yl)oxy]- |
| 4,9-Bis[(3-methyl-2-buten-1-yl)oxy]-7H-furo[3,2-g]chromen-7-one |
