CAS 124387-19-5|5(6)-Carboxyfluorescein Diacetate

Introduction:Basic information about CAS 124387-19-5|5(6)-Carboxyfluorescein Diacetate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name5(6)-Carboxyfluorescein Diacetate
CAS Number124387-19-5Molecular Weight460.39
Density/Boiling Point/
Molecular FormulaC25H16O9Melting Point/
MSDSChineseUSAFlash Point/

Names

Name5(6)-Carboxyfluorescein diacetate
SynonymMore Synonyms

5(6)-Carboxyfluorescein Diacetate BiologicalActivity

Description5(6)-CFDA is a cell-permeant esterase substrate that can serve as a viability probe that measures both enzymatic activity, which is require to activate its fluorescence, and cell-membrane integrity, which is required for intracellular retention of their fluorescent product.
Related CatalogSignaling Pathways >>Others >>OthersDye ReagentsResearch Areas >>Others
References

[1]. Yang T, et al. A novel nonradioactive CFDA assay to monitor the cellular immune response in myeloid leukemia. Immunobiology. 2013 Apr;218(4):548-53.

[2]. Card SD, et al. Assessment of fluorescein-based fluorescent dyes for tracing Neotyphodium endophytes in planta. Mycologia. 2013 Jan-Feb;105(1):221-9.

[3]. Fang X, et al. Bone marrow-derived endothelial progenitor cells are involved in aneurysm repair in rabbits. J Clin Neurosci. 2012 Sep;19(9):1283-6.

Chemical & Physical Properties

Molecular FormulaC25H16O9
Molecular Weight460.39
PSA250.86000
LogP7.60680
Storage condition2-8℃

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard CodesXn
RIDADRNONH for all modes of transport

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Synonyms

3',6'-diacetyloxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-4-carboxylic acid,3',6'-diacetyloxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylic acid
5(6)-Carboxy-di-O-acetylfluorescein
3',6'-Diacetoxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-6-carboxylic acid - 3',6'-diacetoxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-7-carboxylic acid (1:1)
Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid, 3',6'-bis(acetyloxy)-3-oxo-, compd. with 3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-7-carboxylic acid (1:1)
5(6)-CFDA
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