CAS 35218-75-8|Tetraphenylporphyrin Tetrasulfonic Acid Hydrate
| Common Name | Tetraphenylporphyrin Tetrasulfonic Acid Hydrate | ||
|---|---|---|---|
| CAS Number | 35218-75-8 | Molecular Weight | 934.989 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | / |
| Molecular Formula | C44H30N4O12S4 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | tpps |
|---|---|
| Synonym | More Synonyms |
BiologicalActivity
| Description | TPPS can be used as a non-cytotoxic probe for detecting tumor location[1]. |
|---|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
| In Vitro | TPPS (0-20 μg/mL) shows no toxicity in Vero and HEp-2 cells in vitro and predominantly locates in the soluble and protein fractions in cells[1]. |
| In Vivo | TPPS4 shows the highest tumor to tissue ratios after 96 hours injection with a dose dependent manner[2]. TPPS4 appears to be cleared through the kidneys and absolute concentrations there are reduced with increasing time after injection[2]. |
| References | [1]. Austen JD, et al. Intracellular localization of meso-Tetra(p-sulfophenyl)porphine: a potential tumor localizing agent. Cancer Treat Rep. 1978 Apr;62(4):511-8. [2]. https://pubmed.ncbi.nlm.nih.gov/201378/ |
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Molecular Formula | C44H30N4O12S4 |
| Molecular Weight | 934.989 |
| Exact Mass | 934.074280 |
| PSA | 307.30000 |
| LogP | 5.01 |
| Index of Refraction | 1.724 |
| InChIKey | PBHVCRIXMXQXPD-UHFFFAOYSA-N |
| SMILES | O=S(=O)(O)c1ccc(-c2c3nc(c(-c4ccc(S(=O)(=O)O)cc4)c4ccc([nH]4)c(-c4ccc(S(=O)(=O)O)cc4)c4nc(c(-c5ccc(S(=O)(=O)O)cc5)c5ccc2[nH]5)C=C4)C=C3)cc1 |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | DB7339000 |
Articles30
More Articles| Femtosecond to second studies of a water-soluble porphyrin derivative in chemical and biological nanocavities. Langmuir 28(9) , 4363-72, (2012) The interactions of 5,10,15,20-tetrakis(4-sulfonatophenyl)-porphyrin (TSPP) with a quaternary ammonium modified β-cyclodextrin (QA-β-CD) and human serum albumin (HSA) protein in aqueous solutions at p... | |
| Preferential solvation and solvation shell composition of free base and protonated 5, 10, 15, 20-tetrakis(4-sulfonatophenyl)porphyrin in aqueous organic mixed solvents. Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 83(1) , 213-20, (2011) The solvatochromic properties of the free base and the protonated 5, 10, 15, 20-tetrakis(4-sulfonatophenyl)porphyrin (TPPS) were studied in pure water, methanol, ethanol (protic solvents), dimethylsul... | |
| Interaction of monosulfonate tetraphenyl porphyrin (H2TPPS1) with plant-esterase: determination of the binding mechanism by spectroscopic methods. Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 78(5) , 1349-55, (2011) The interaction of monosulfonate tetraphenyl porphyrin (H(2)TPPS(1)) with plant-esterase was investigated using fluorescence and UV-vis absorption spectroscopy. Fluorescence quenching, from which the ... |
Synonyms
| tetraphenylporphinesulfonate |
| MFCD00070632 |
| tpps4 |
| (Tetraphenylporphyrin Tetrasulfonic Acid Hydrate) |
| 4,4',4'',4'''-(5,10,15,20-Porphyrintetrayl)tetrabenzenesulfonic acid |
| Benzenesulfonic acid, 4,4',4'',4'''-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis- |
| meso-Tetraphenylporphine-4,4',4 |
| meso-tetraphenylporphine-4,4',4'',4'''-tetrasulfonic acid |
| TSPP |
| 5,10,15,20-Tetrakis(4-sulfophenyl)porphyrin Hydrate |
| 5,10,15,20-tetraphenyl-21H,23H-perphine-4,4',4'',4'''-tetrasulfonic acid |
| 4,4',4'',4'''-porphyrin-5,10,15,20-tetrayltetrabenzenesulfonic acid |
