CAS 68189-43-5|Piperazine-1,4-bis(2-hydroxypropanesulfonic acid) dihydrate

Introduction：Basic information about CAS 68189-43-5|Piperazine-1,4-bis(2-hydroxypropanesulfonic acid) dihydrate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	Piperazine-1,4-bis(2-hydroxypropanesulfonic acid) dihydrate
CAS Number	68189-43-5	Molecular Weight	362.420
Density	1.6±0.1 g/cm3	Boiling Point	/
Molecular Formula	C₁₀H₂₂N₂O₈S₂	Melting Point	320°C
MSDS	/	Flash Point	/

Names

Name	Piperazine-1,4-bis(2-hydroxypropanesulfonic acid) dihydrate
Synonym	More Synonyms

BiologicalActivity

Description	POPSO is a zwitterionic buffer, increases osmolality and shows marked inhibition of anion uniport. POPSO inhibits chloride uniport with an IC50 value of 24 mM. POPSO enhances copper uptake and toxicity in alga, impairs mitochondrial inner membrane. The working pH range of POPSO sesquisodium salt is 7.2-8.5[1][2][3].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
References	[1]. Ng LT, et al. Effect of buffers and osmolality on anion uniport across the mitochondrial inner membrane. Biochim Biophys Acta. 1993 Jun 10;1143(1):29-37. [2]. Vasconcelos, et al. Influence of zwitterionic pH buffers on the bioavailability and toxicity of copper to the alga Amphidinium carterae. 2009 Nov;19(10):2542-2550. [3]. Kebede N, et al. Electrogenerated chemiluminescence of tris(2,2' bipyridine)ruthenium(II) using common biological buffers as co-reactant, pH buffer and supporting electrolyte. Analyst. 2015 Nov 7;140(21):7142-5.

Description

POPSO is a zwitterionic buffer, increases osmolality and shows marked inhibition of anion uniport. POPSO inhibits chloride uniport with an IC50 value of 24 mM. POPSO enhances copper uptake and toxicity in alga, impairs mitochondrial inner membrane. The working pH range of POPSO sesquisodium salt is 7.2-8.5[1][2][3].

Related Catalog

Research Areas >>OthersSignaling Pathways >>Others >>Others

References

[1]. Ng LT, et al. Effect of buffers and osmolality on anion uniport across the mitochondrial inner membrane. Biochim Biophys Acta. 1993 Jun 10;1143(1):29-37.

[2]. Vasconcelos, et al. Influence of zwitterionic pH buffers on the bioavailability and toxicity of copper to the alga Amphidinium carterae. 2009 Nov;19(10):2542-2550.

[3]. Kebede N, et al. Electrogenerated chemiluminescence of tris(2,2' bipyridine)ruthenium(II) using common biological buffers as co-reactant, pH buffer and supporting electrolyte. Analyst. 2015 Nov 7;140(21):7142-5.

Chemical & Physical Properties

Density	1.6±0.1 g/cm3
Melting Point	320°C
Molecular Formula	C₁₀H₂₂N₂O₈S₂
Molecular Weight	362.420
Exact Mass	362.081757
PSA	172.44000
LogP	-4.05
Index of Refraction	1.593
InChIKey	LVQFQZZGTZFUNF-UHFFFAOYSA-N
SMILES	O=S(=O)(O)CC(O)CN1CCN(CC(O)CS(=O)(=O)O)CC1
Storage condition	Store at RT.
Water Solubility	1 M NaOH: 0.1 M, clear, colorless

Safety Information

Hazard Codes	T
Risk Phrases	21-23/24/25-25-36/37/38
Safety Phrases	S22-S24/25
WGK Germany	3
HS Code	2933599090

Customs

HS Code	2933599090
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

3,3'-Piperazine-1,4-diylbis(2-hydroxypropane-1-sulfonic acid)

MFCD00038350

3,3'-(1,4-Piperazinediyl)bis(2-hydroxy-1-propanesulfonic acid)

EINECS 269-199-1

2-hydroxy-3-[4-(2-hydroxy-3-sulfopropyl)piperazin-1-yl]propane-1-sulfonic acid

1,4-Piperazinedipropanesulfonic acid, β,β'-dihydroxy-

Recommended......