Introduction：Basic information about CAS 68399-81-5|TAPSO, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | TAPSO |
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| CAS Number | 68399-81-5 | Molecular Weight | 259.277 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C7H17NO7S | Melting Point | 224-229 °C (dec.) |
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| MSDS | ChineseUSA | Flash Point | / |
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| Symbol |
GHS07 | Signal Word | Warning |
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Names
| Name | 3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]-2-hydroxypropane-1-sulfonic acid |
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| Synonym | More Synonyms |
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TAPSO BiologicalActivity
| Description | TAPSO is a common biological buffer, a pH stabilization reagent, with effective pH ranging from 7-8, and pKa values ranging from 7.5–9.0. TAPSO contains Tris groups and exhibits quite reactive activity with zwitterionic glycine peptides[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. Machado CM, et al. Interpretation of non-Nernstian slopes in graphic analysis of data collected in pH range close to deprotonation of a ligand Part I. A glass electrode potentiometric and polarographic study of Cd-(TAPSO)x-(OH)y and Zn-(TAPSO)x-(OH)y systems. Talanta. 2006 Jan 15;68(3):819-30. |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Melting Point | 224-229 °C (dec.) |
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| Molecular Formula | C7H17NO7S |
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| Molecular Weight | 259.277 |
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| Exact Mass | 259.072571 |
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| PSA | 155.70000 |
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| LogP | -2.64 |
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| Index of Refraction | 1.598 |
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| InChIKey | RZQXOGQSPBYUKH-UHFFFAOYSA-N |
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| SMILES | O=S(=O)(O)CC(O)CNC(CO)(CO)CO |
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| Water Solubility | soluble |
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Safety Information
| Symbol |
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H315-H319-H335 |
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| Precautionary Statements | P261-P305 + P351 + P338 |
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| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
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| Hazard Codes | Xi:Irritant; |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S26-S36 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| HS Code | 2922199090 |
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Customs
| HS Code | 2922199090 |
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| Summary | 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| 3-[(1,3-Dihydroxy-2-propanyl)(hydroxymethyl)amino]-2-hydroxy-1-propanesulfonic acid |
| TAPSO |
| 3,3-dibromo-tetrahydro-pyran-2-ol |
| 3,3-Dibrom-2-hydroxytetrahydropyran |
| MFCD00038352 |
| 1-Propanesulfonic acid, 2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]- |
| 3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}-2-hydroxypropane-1-sulfonic acid |
| UNII:45Q4J0071U |
| 2-Hydroxy-3-{[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino}propane-1-sulfonic acid |
| 2-Hydroxy-3.3-dibrom-tetrahydro-pyran |
| TAPSO (buffer) |
| 3-[N-Tris(hydroxymethyl)methylamino]-2-hydroxypropane-sulfonic acid |
| EINECS 269-993-8 |
| 1-Propanesulfonic acid, 2-hydroxy-3-[[2-hydroxy-1-(hydroxymethyl)ethyl](hydroxymethyl)amino]- |
| 3-{[1,3-Dihydroxy-2-(hydroxymethyl)-2-propanyl]amino}-2-hydroxy-1-propanesulfonic acid |
