Introduction：Basic information about CAS 150-25-4|N,N-bis(2-hydroxyethyl)glycine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N,N-bis(2-hydroxyethyl)glycine |
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| CAS Number | 150-25-4 | Molecular Weight | 163.17 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 388.5±27.0 °C at 760 mmHg |
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| Molecular Formula | C6H13NO4 | Melting Point | 190 °C (dec.)(lit.) |
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| MSDS | ChineseUSA | Flash Point | 188.8±23.7 °C |
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Names
| Name | N,N-bis(2-hydroxyethyl)glycine |
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| Synonym | More Synonyms |
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N,N-bis(2-hydroxyethyl)glycine BiologicalActivity
| Description | Bicine is a useful buffer in the range of physiological interest. Bicine is a derivative of the simple amino acid glycine[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. Taha M, et al. Mixed-ligand complex formation equilibria of cobalt (II), nickel (II), and copper (II) with N, N-bis (2-hydroxyethyl) glycine (bicine) and some amino acids[J]. Journal of Chemical & Engineering Data, 2005, 50(1): 157-163. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 388.5±27.0 °C at 760 mmHg |
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| Melting Point | 190 °C (dec.)(lit.) |
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| Molecular Formula | C6H13NO4 |
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| Molecular Weight | 163.17 |
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| Flash Point | 188.8±23.7 °C |
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| Exact Mass | 163.084457 |
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| PSA | 81.00000 |
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| LogP | -0.47 |
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| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
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| Index of Refraction | 1.526 |
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| InChIKey | FSVCELGFZIQNCK-UHFFFAOYSA-N |
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| SMILES | O=C(O)CN(CCO)CCO |
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| Storage condition | 2-8°C |
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| Water Solubility | soluble |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- MB9700000
- CHEMICAL NAME :
- Glycine, N,N-dihydroxyethyl-
- CAS REGISTRY NUMBER :
- 150-25-4
- BEILSTEIN REFERENCE NO. :
- 1769362
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C6-H13-N-O4
- MOLECULAR WEIGHT :
- 163.20
- WISWESSER LINE NOTATION :
- QV1N2Q2Q
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1540 mg/kg
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
- REFERENCE :
- REPMBN Revue d'Epidemiologie, Medecine Sociale et Sante Publique. (Masson Editeur, 120 Blvd. Saint-Germain, F-75280 Paris Cedex O6, France) V.1- 1953- Volume(issue)/page/year: 10,391,1962 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9723 No. of Facilities: 130 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 1828 (estimated) No. of Female Employees: 1552 (estimated)
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xn |
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| Risk Phrases | R20/21/22 |
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| Safety Phrases | S24/25 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| RTECS | MB9700000 |
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| HS Code | 29225000 |
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Customs
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Synonyms
| Diethylolglycine |
| N,N-Bis(2-hydroxyethyl)glycine,BICINE,PEG Grid Screening |
| Di(hydroxyethyl)glycine |
| Glycine, N, N-dihydroxyethyl- |
| N,N-Dihydroxyethyl glycine |
| bicine buffer |
| Bis(2-Hydroxyethyl)glycine |
| Bicine |
| BICINE[N,N-Di(2-hydroxyethyl)glycine] |
| EINECS 205-755-1 |
| Bicene |
| N,N-Bis(b-hydroxyethyl)glycine |
| N,N-Di(2-hydroxyethyl)glycine |
| Glycine, N,N-bis(2-hydroxyethyl)- |
| Diethanolglycine |
| 2-[bis(2-hydroxyethyl)amino]acetic acid |
| 2-HxG |
| 2-(bis(2-hydroxyethyl)amino)acetic acid |
| N,N-Bis(β-hydroxyethyl)glycine |
| MFCD00004295 |
| (Bis(2-hydroxyethyl)amino)acetic Acid |
| Glycine, N,N-bis (2-hydroxyethyl)- |
| N,N-dihydroxyethylglycine |
| N,N-Bis(2-hydroxyethyl)aminoacetic acid |
| N,N-Bis(hydroxyethyl)glycine |
| N,N-Bis(2-hydroxyethyl)glycine |
| N,N-Di(2-hydroxyethyl)glycine [Good's buffer component |
| N,N-Di(hydroxyethyl)aminoacetic Acid |
| Diethanol glycine |
| N,N-Bis(2-hydroxyethyl)glycine (Bicine) |
| Dihydroxyethylglycine |
