Introduction：Basic information about CAS 54827-17-7|Tetramethylbenzidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Tetramethylbenzidine |
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| CAS Number | 54827-17-7 | Molecular Weight | 240.343 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 368.6±37.0 °C at 760 mmHg |
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| Molecular Formula | C16H20N2 | Melting Point | 168-171 °C(lit.) |
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| MSDS | USA | Flash Point | 210.8±26.0 °C |
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Names
| Name | Tetramethylbenzidine |
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| Synonym | More Synonyms |
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Tetramethylbenzidine BiologicalActivity
| Description | 3,3’,5,5’-Tetramethylbenzidine(TMB) is a chromogenic substrate used in staining procedures in immunohistochemistry as well as being a visualising reagent used in enzyme-linked immunosorbent assays (ELISA). |
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| Related Catalog | Signaling Pathways >>Others >>OthersDye ReagentsResearch Areas >>Others |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 368.6±37.0 °C at 760 mmHg |
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| Melting Point | 168-171 °C(lit.) |
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| Molecular Formula | C16H20N2 |
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| Molecular Weight | 240.343 |
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| Flash Point | 210.8±26.0 °C |
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| Exact Mass | 240.162643 |
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| PSA | 52.04000 |
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| LogP | 3.40 |
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| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
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| Index of Refraction | 1.618 |
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| InChIKey | UAIUNKRWKOVEES-UHFFFAOYSA-N |
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| SMILES | Cc1cc(-c2cc(C)c(N)c(C)c2)cc(C)c1N |
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| Storage condition | 2-8°C |
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| Stability | Stable, but moisture sensitive and may be light sensitive. Incompatible with water, strong oxidizing agents. |
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| Water Solubility | Slightly soluble. |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DV2300000
- CHEMICAL NAME :
- (1,1'-Biphenyl)-4,4-diamine, 3,3',5,5'-tetramethyl-
- CAS REGISTRY NUMBER :
- 54827-17-7
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C16-H20-N2
- MOLECULAR WEIGHT :
- 240.38
- WISWESSER LINE NOTATION :
- ZR B1 F1 DR DZ C1 E1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 135 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - quail
- DOSE/DURATION :
- >316 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- Micronucleus test
MUTATION DATA - TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - mouse Lymphocyte
- DOSE/DURATION :
- 30700 ug/L
- REFERENCE :
- EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 12(Suppl 13),37,1988
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Safety Information
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
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| Hazard Codes | Xi:Irritant |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S26-S36-S36/37 |
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| RIDADR | UN 2796 8/PG 2 |
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| WGK Germany | 3 |
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| RTECS | DV2300000 |
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| Hazard Class | 8.0 |
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| HS Code | 29215990 |
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Customs
| HS Code | 2921590090 |
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| Summary | 2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| 3355TMB |
| 3,3,5',5'-Tetramethylbenzidine |
| UNII-3B3T5CB8EO |
| TMB/H |
| TMB-E |
| TMB/M |
| 3,3’,5,5’-tetramethylbenzidine |
| EINECS 259-364-6 |
| TMB |
| BM BLUE |
| 3,3',5,5'-Tetramethyl-4,4'-biphenyldiamine |
| 3,3',5,5'-tetramethyl-4,4'-diamino-1,1'-biphenyl |
| TMB QUICK |
| 3,3',5,5'-tetramethylbenzidine |
| Tmbz |
| MFCD00007748 |
| 3,3',5,5'-Tetramethylbiphenyl-4,4'-diamine |
| 3,5,3',5'-tetramethylbenzidine |
| TMB EASY |
| TMB-B |
| [1,1'-Biphenyl]-4,4'-diamine, 3,3',5,5'-tetramethyl- |
