CAS 54029-12-8|Albendazole Oxide
| Common Name | Albendazole Oxide | ||
|---|---|---|---|
| CAS Number | 54029-12-8 | Molecular Weight | 281.331 |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 357.3ºC at 760 mmHg |
| Molecular Formula | C12H15N3O3S | Melting Point | 154-156ºC |
| MSDS | ChineseUSA | Flash Point | 169.9ºC |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | albendazole S-oxide |
|---|---|
| Synonym | More Synonyms |
Albendazole Oxide BiologicalActivity
| Description | Albendazole sulfoxide (Ricobendazole), the main active metabolite of Albendazole, exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes[1]. |
|---|---|
| Related Catalog | Research Areas >>Infection |
| References | [1]. Gokhan Adas,, et al. Use of albendazole sulfoxide, albendazole sulfone, and combined solutions as scolicidal agents on hydatid cysts (in vitro study). |
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 357.3ºC at 760 mmHg |
| Melting Point | 154-156ºC |
| Molecular Formula | C12H15N3O3S |
| Molecular Weight | 281.331 |
| Flash Point | 169.9ºC |
| Exact Mass | 281.083405 |
| PSA | 103.29000 |
| LogP | 0.91 |
| Index of Refraction | 1.659 |
| InChIKey | VXTGHWHFYNYFFV-UHFFFAOYSA-N |
| SMILES | CCCS(=O)c1ccc2nc(NC(=O)OC)[nH]c2c1 |
| Storage condition | -20°C Freezer |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn |
| Risk Phrases | 22 |
| RIDADR | NONH for all modes of transport |
| RTECS | FD1080000 |
Articles32
More Articles| Azole antifungal inhibition of buprenorphine, methadone and oxycodone in vitro metabolism. J. Anal. Toxicol. 39 , 374-86, (2015) Opioid-related mortality rates have escalated. Drug interactions may increase blood concentrations of the opioid. We therefore used human liver microsomes (HLMs) and cDNA-expressed human cytochrome P4... | |
| Validation of a streamlined multiclass, multiresidue method for determination of veterinary drug residues in bovine muscle by liquid chromatography-tandem mass spectrometry. Anal. Bioanal. Chem 407 , 4423-35, (2015) Multiclass, multiresidue methods are becoming increasingly popular in regulatory monitoring programs due to their increased analytical scope and laboratory efficiency. In this work, we report the deve... | |
| The transport of albendazole and albendazole sulphoxide in the lancet fluke (Dicrocoelium dendriticum). Vet. Parasitol. 176(1) , 27-33, (2011) Albendazole (ABZ) is one of the most important benzimidazole compounds possessing high activity against the lancet fluke, Dicrocoelium dendriticum. ABZ sulphoxide (ABZ.SO) is the main molecule present... |
Synonyms
| Rycobendazole |
| Carbamic acid, N-[5-(propylsulfinyl)-1H-benzimidazol-2-yl]-, methyl ester |
| carbamic acid, N-[6-(propylsulfinyl)-1H-benzimidazol-2-yl]-, methyl ester |
| MFCD00797922 |
| Albendazole Sulfoxide |
| Albendazole S-oxide |
| Ricobendazole |
| Albendazole sulphoxide |
| Methyl [5-(propylsulfinyl)-1H-benzimidazol-2-yl]carbamate |
| Albendazole oxide |
