CAS 122-51-0|Triethyl orthoformate
| Common Name | Triethyl orthoformate | ||
|---|---|---|---|
| CAS Number | 122-51-0 | Molecular Weight | 148.200 |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 142.5±0.0 °C at 760 mmHg |
| Molecular Formula | C7H16O3 | Melting Point | −76 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 30.0±0.0 °C |
| Symbol | GHS02 | Signal Word | Warning |
Names
| Name | Triethyl orthoformate |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 142.5±0.0 °C at 760 mmHg |
| Melting Point | −76 °C(lit.) |
| Molecular Formula | C7H16O3 |
| Molecular Weight | 148.200 |
| Flash Point | 30.0±0.0 °C |
| Exact Mass | 148.109940 |
| PSA | 27.69000 |
| LogP | 2.14 |
| Vapour density | 5.11 (vs air) |
| Vapour Pressure | 7.0±0.2 mmHg at 25°C |
| Index of Refraction | 1.400 |
| InChIKey | GKASDNZWUGIAMG-UHFFFAOYSA-N |
| SMILES | CCOC(OCC)OCC |
| Water Solubility | 1.35 g/L |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,352,1986
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,352,1986 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7060 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4000 ppm/8H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 20 mL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- >10 mL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,917,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84005 No. of Facilities: 5 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 20 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84005 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1582 (estimated) No. of Female Employees: 323 (estimated)
Safety Information
| Symbol | GHS02 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H226 |
| Precautionary Statements | P210-P403 + P235 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R10;R36/38 |
| Safety Phrases | S16-S26-S37/39 |
| RIDADR | UN 2524 3/PG 3 |
| WGK Germany | 1 |
| RTECS | RM6475000 |
| Packaging Group | III |
| Hazard Class | 3 |
| HS Code | 2915130000 |
Customs
| HS Code | 2909199090 |
|---|---|
| Summary | 2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0% |
Articles5
More Articles| Triethyl orthoformate mediated a novel crosslinking method for the preparation of hydrogels for tissue engineering applications: characterization and in vitro cytocompatibility analysis. Mater. Sci. Eng. C. Mater. Biol. Appl. 56 , 154-64, (2015) This paper describes the development of a new crosslinking method for the synthesis of novel hydrogel films from chitosan and PVA for potential use in various biomedical applications. These hydrogel m... | |
| Geometry and Spin Change at the Heart of a Cobalt(II) Complex: A Special Case of Solvatomorphism. Chemistry 21 , 9474-81, (2015) Structural analysis and spectroscopic methods revealed a special case of solvatomorphism: hydrogen-bonding-induced geometry and spin change within a same N,O-(bis)chelate of cobalt(II). Solid-state st... | |
| An efficient synthesis of achiral and chiral 1,2,4-triazolium salts: bench stable precursors for N-heterocyclic carbenes. J. Org. Chem. 70(14) , 5725-8, (2005) [reaction: see text] The promising utility of triazolyl N-heterocyclic carbene catalysts in umpolung aldehyde chemistry requires a straightforward reliable synthesis from readily available materials. ... |
Synonyms
| 1,1,1-Triethoxymethane |
| triethoxymethane |
| EINECS 204-550-4 |
| Ethyl orthoformate |
| UNII:355LRR361Q |
| Orthopropionic Acid Triethyl Ester |
| Orthoformic acid, triethyl ester |
| 4-02-00-00025 (Beilstein Handbook Reference) |
| ortho-formic acid triethyl ester |
| (Diethoxymethoxy)ethane |
| Formylolate |
| MFCD00009230 |
| 1,1,1-Triethoxypropane |
| ethyl-orthoformate |
| triethyl ortho formate |
| Triethyl orthoformate |
| Orthoformic acid triethyl ester |
| ETHYL-O-FORMATE |
| Ethyl orthoformate [UN2524] [Flammable liquid] |
| 1,1',1''-[methanetriyltris(oxy)]triethane |
| AETHON |
| ETHONE |
| triethylorthoformate |
| TEOF |
| Triethoxmethane |
| Ethyl Orthopropionate |
| Methane, triethoxy- |
| triethoxy-methan |
| Triethyl Orthopropionate |
| Propane, 1,1,1-triethoxy- |
| Ethane, 1,1',1''-[methylidynetris(oxy)]tris- |
| ortho-formic |
