CAS 5144-89-8|o-Phenanthroline monohydrate
| Common Name | o-Phenanthroline monohydrate | ||
|---|---|---|---|
| CAS Number | 5144-89-8 | Molecular Weight | 198.221 |
| Density | 1.10 | Boiling Point | 365.1ºC at 760 mmHg |
| Molecular Formula | C12H10N2O | Melting Point | 100-104 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 164.8ºC |
| Symbol | GHS06, GHS09 | Signal Word | Danger |
Names
| Name | 1,10-Phenanthroline hydrate |
|---|---|
| Synonym | More Synonyms |
o-Phenanthroline monohydrate BiologicalActivity
| Description | o-Phenanthroline monohydrate (1,10-Phenanthroline monohydrate), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline monohydrate forms a red chelate with Fe2+ that absorbs maximally at 510 nm[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Guan NanMu, et al. Synergistic inhibition between o-phenanthroline and chloride ion on cold rolled steel corrosion in phosphoric acid. Materials Chemistry and Physics Volume 86, Issue 1, 15 July 2004, Pages 59-68. |
Chemical & Physical Properties
| Density | 1.10 |
|---|---|
| Boiling Point | 365.1ºC at 760 mmHg |
| Melting Point | 100-104 °C(lit.) |
| Molecular Formula | C12H10N2O |
| Molecular Weight | 198.221 |
| Flash Point | 164.8ºC |
| Exact Mass | 198.079315 |
| PSA | 35.01000 |
| LogP | 2.71870 |
| InChIKey | PPQJCISYYXZCAE-UHFFFAOYSA-N |
| SMILES | O.c1cnc2c(c1)ccc1cccnc12 |
| Storage condition | Store at RT. |
| Stability | Stable. Incompatible with iron, other heavy metals, strong oxidizing agents, strong acids. |
| Water Solubility | <0.01 g/100 mL at 21 ºC |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - mouse Ascites tumor
- DOSE/DURATION :
- 5 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 40,4092,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7001 No. of Facilities: 63 (estimated) No. of Industries: 6 No. of Occupations: 4 No. of Employees: 364 (estimated) No. of Female Employees: 27 (estimated)
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - mouse Ascites tumor
- DOSE/DURATION :
- 5 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 40,4092,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7001 No. of Facilities: 63 (estimated) No. of Industries: 6 No. of Occupations: 4 No. of Employees: 364 (estimated) No. of Female Employees: 27 (estimated)
Safety Information
| Symbol | GHS06, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H410 |
| Precautionary Statements | P273-P301 + P310-P501 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
| Hazard Codes | T:Toxic |
| Risk Phrases | R25;R50/53 |
| Safety Phrases | S45-S60-S61 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | SF8437000 |
| Packaging Group | III |
| Hazard Class | 6.1 |
| HS Code | 29339990 |
Customs
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 1,10-Phenanthroline hydrate (1:1) |
| 1,10-PHENANTHROLINE H2O |
| 1,10-Phenanthroline hydrate |
| 1,10-phehanthroline monohydrate |
| EINECS 200-629-2 |
| 1,10-phenanthroline monohydrate |
| 4,5-Phenanthrolinemonohydrate |
| O-PHENANTHROLINE MONOHYDRATE |
| ORTHO-PHENANTHROLINE |
| 1,10-phenanthroline-hydrate |
| MFCD00149973 |
| 1,10'-phenahthroline monohydrate |
| 1,10-Phenanthroline, hydrate (1:1) |
| 1,10-PHENANTHROLINE AR |
| O-PHENANTHROLINE HYDRATE |
| 1,10-phenanthrolinemonorate |
| 1,10-PHENANTHROLINE AR (H2O) |
