CAS 51776-33-1|LHRH (4-10) acetate salt

Introduction：Basic information about CAS 51776-33-1|LHRH (4-10) acetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. LHRH (4-10) acetate salt BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	LHRH (4-10) acetate salt
CAS Number	51776-33-1	Molecular Weight	747.84200
Density	/	Boiling Point	/
Molecular Formula	C₃₃H₅₃N₁₁O₉	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	1-[2-[[2-[[2-[[2-[(2-amino-3-hydroxypropanoyl)amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-(2-amino-2-oxoethyl)pyrrolidine-2-carboxamide$GLP-HIS-TYR-SER-LEU-GLU-TRP-LYS-PRO-GLY-NH2
Synonym	More Synonyms

LHRH (4-10) acetate salt BiologicalActivity

Description	LH-RH (4-10) is a heptapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (4-10) produced in macrophages and type II pneumocytes[1].
Related Catalog	Signaling Pathways >>GPCR/G Protein >>GNRH ReceptorResearch Areas >>Endocrinology
In Vitro	The formation of LHRH 4-10, LHRH 7-10, and LHRH 6-10Co-incubation are inhibited by known enzyme inhibitors including Captopril (HY-B0368) (an ACE inhibitor), Thiorphan (HY-W013375) (an EP24.11 inhibitor), and Ethylenediaminetetraacetic acid (HY-Y0682) (an EP24.15 inhibitor)[1]. LH-RH (4-10) inhibits the binding of 125I-labeled GnRH to monoclonal antibody P81662 with an IC50 value of 23 pM[2].

Chemical & Physical Properties

Molecular Formula	C₃₃H₅₃N₁₁O₉
Molecular Weight	747.84200
Exact Mass	747.40300
PSA	337.28000
LogP	0.21070
InChIKey	ASNHUSJQZWXBOG-UHFFFAOYSA-N
SMILES	CC(C)CC(NC(=O)CNC(=O)C(Cc1ccc(O)cc1)NC(=O)C(N)CO)C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NCC(N)=O

Safety Information

Hazard Codes	T
Risk Phrases	60
Safety Phrases	53-22-36/37/39-45
WGK Germany	3

Synonyms

Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2

Luteinizing hormone releasing hormone Fragment 4-10

LH-RH Fragment 4-10

LHRH (4-10)

H-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2

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