CAS 156251-01-3|MART-1 (26-35) (human) trifluoroacetate salt

Introduction：Basic information about CAS 156251-01-3|MART-1 (26-35) (human) trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	MART-1 (26-35) (human) trifluoroacetate salt
CAS Number	156251-01-3	Molecular Weight	943.096
Density	1.2±0.1 g/cm3	Boiling Point	1358.4±65.0 °C at 760 mmHg
Molecular Formula	C₄₂H₇₄N₁₀O₁₄	Melting Point	/
MSDS	/	Flash Point	775.3±34.3 °C

Names

Name	Melan-A, MART 1 (26-35),EAAGIGILTV
Synonym	More Synonyms

BiologicalActivity

Description	MART-1 (26-35) is amino acid residue 26 to 35 of MART-1 protein.
Related Catalog	Signaling Pathways >>Others >>OthersPeptidesResearch Areas >>Inflammation/Immunology
In Vitro	MART-1 (Melan-A) gene is 18 kb long and comprises five exons. It is expressed in most melanoma tumor samples, and among normal cells, only in melanocytes[1]. In cancer immunotherapy, epitopes and variants derived from the MART-1/Melan-A protein are widely used as clinical vaccines. The epitopes spanning amino acid residues 26–35 and 27–35 from the MART-1/Melan-A protein, highly expressed in melanoma cells, provide a prime example of T cell recognition of multiple peptides and the use of peptide variants designed to elicit altered immunological responses[2].
References	[1]. Coulie PG, et al. A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas. J Exp Med. 1994 Jul 1;180(1):35-42. [2]. Borbulevych OY, et al. Structures of MART-126/27-35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition. J Mol Biol. 2007 Oct 5;372(5):1123-36.

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	1358.4±65.0 °C at 760 mmHg
Molecular Formula	C₄₂H₇₄N₁₀O₁₄
Molecular Weight	943.096
Flash Point	775.3±34.3 °C
Exact Mass	942.538574
PSA	382.75000
LogP	1.19
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.527
InChIKey	TUIOKRGNEZUFAI-UHFFFAOYSA-N
SMILES	CCC(C)C(NC(=O)CNC(=O)C(C)NC(=O)C(C)NC(=O)C(N)CCC(=O)O)C(=O)NCC(=O)NC(C(=O)NC(CC(C)C)C(=O)NC(C(=O)NC(C(=O)O)C(C)C)C(C)O)C(C)CC

Synonyms

Melan-A,MART 1 (26-35)

ANTIGEN SK29-AA (26-35) (HUMAN)

L-α-Glutamyl-L-alanyl-L-alanylglycyl-L-isoleucylglycyl-L-isoleucyl-L-leucyl-L-threonyl-L-valine

MART-1 (26-35) (HUMAN)

GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL

ANTIGEN LB39-AA (26-35) (HUMAN)

MELAN-A PROTEIN (26-35) (HUMAN)

EAAGIGILTV

L-Valine, L-α-glutamyl-L-alanyl-L-alanylglycyl-L-isoleucylglycyl-L-isoleucyl-L-leucyl-L-threonyl-

MART-1 (26-35),human (3)

MELAN-A

MART 1 (26-35)

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