Introduction:Basic information about CAS 144025-82-1|PACAP-38 (16-38) (human, chicken, mouse, ovine, porcine, rat) trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | PACAP-38 (16-38) (human, chicken, mouse, ovine, porcine, rat) trifluoroacetate salt |
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| CAS Number | 144025-82-1 | Molecular Weight | 2720.33 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C123H215N39O28S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | PACAP-38: 16-38, human, ovine, rat |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | PACAP-38 (16-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production[1]. PACAP is a potent activator of cAMP formation[2]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
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| References | [1]. Braas KM, et al. Pituitary adenylate cyclase-activating polypeptides, PACAP-38 and PACAP-27, regulation of sympathetic neuron catecholamine, and neuropeptide Y expression through activation of type I PACAP/VIP receptor isoforms. Ann N Y Acad Sci. 1996 Dec 26;805:204-16. [2]. Lania A, et al. Mechanism of action of pituitary adenylate cyclase-activating polypeptide (PACAP) in human nonfunctioning pituitary tumors. J Neuroendocrinol. 1995 Sep;7(9):695-702. |
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Chemical & Physical Properties
| Molecular Formula | C123H215N39O28S |
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| Molecular Weight | 2720.33 |
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| Exact Mass | 2718.63000 |
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| PSA | 1184.26000 |
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| LogP | 9.25750 |
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| InChIKey | JNNCPZMLQNUITC-UHFFFAOYSA-N |
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| SMILES | CSCCC(NC(=O)C(N)CCC(N)=O)C(=O)NC(C)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCCN)C(=O)NC(CCC(N)=O)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(CC(N)=O)C(=O)NC(CCCCN)C(N)=O)C(C)C)C(C)C)C(C)C |
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Synonyms
| PACAP-38 (16-38) (HUMAN,CHICKEN,MOUSE,OVINE,PORCINE,RAT) |
| H-GLN-MET-ALA-VAL-LYS-LYS-TYR-LEU-ALA-ALA-VAL-LEU-GLY-LYS-ARG-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2 |
| PACAP (16-38) (HUMAN,OVINE,RAT) |
| Pituitary Adenylate Cyclase Activating Polypeptide-38 (16-38) (huMan,chicken,Mouse,ovine,porcine,rat) |
| PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE-38 (16-38),HUMAN,OVINE,RAT |
| PACAP-38 (16-38),HUMAN,OVINE,RAT |
| PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE (16-38) (HUMAN,OVINE,RAT) |
| GLN-MET-ALA-VAL-LYS-LYS-TYR-LEU-ALA-ALA-VAL-LEU-GLY-LYS-ARG-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2: QMAVKKYLAAVLGKRYKQRVKNK-NH2 |