CAS 144025-82-1|PACAP-38 (16-38) (human, chicken, mouse, ovine, porcine, rat) trifluoroacetate salt

Introduction:Basic information about CAS 144025-82-1|PACAP-38 (16-38) (human, chicken, mouse, ovine, porcine, rat) trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NamePACAP-38 (16-38) (human, chicken, mouse, ovine, porcine, rat) trifluoroacetate salt
CAS Number144025-82-1Molecular Weight2720.33
Density/Boiling Point/
Molecular FormulaC123H215N39O28SMelting Point/
MSDS/Flash Point/

Names

NamePACAP-38: 16-38, human, ovine, rat
SynonymMore Synonyms

BiologicalActivity

DescriptionPACAP-38 (16-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production[1]. PACAP is a potent activator of cAMP formation[2].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease
References

[1]. Braas KM, et al. Pituitary adenylate cyclase-activating polypeptides, PACAP-38 and PACAP-27, regulation of sympathetic neuron catecholamine, and neuropeptide Y expression through activation of type I PACAP/VIP receptor isoforms. Ann N Y Acad Sci. 1996 Dec 26;805:204-16.

[2]. Lania A, et al. Mechanism of action of pituitary adenylate cyclase-activating polypeptide (PACAP) in human nonfunctioning pituitary tumors. J Neuroendocrinol. 1995 Sep;7(9):695-702.

Chemical & Physical Properties

Molecular FormulaC123H215N39O28S
Molecular Weight2720.33
Exact Mass2718.63000
PSA1184.26000
LogP9.25750
InChIKeyJNNCPZMLQNUITC-UHFFFAOYSA-N
SMILESCSCCC(NC(=O)C(N)CCC(N)=O)C(=O)NC(C)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCCN)C(=O)NC(CCC(N)=O)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(CC(N)=O)C(=O)NC(CCCCN)C(N)=O)C(C)C)C(C)C)C(C)C

Synonyms

PACAP-38 (16-38) (HUMAN,CHICKEN,MOUSE,OVINE,PORCINE,RAT)
H-GLN-MET-ALA-VAL-LYS-LYS-TYR-LEU-ALA-ALA-VAL-LEU-GLY-LYS-ARG-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2
PACAP (16-38) (HUMAN,OVINE,RAT)
Pituitary Adenylate Cyclase Activating Polypeptide-38 (16-38) (huMan,chicken,Mouse,ovine,porcine,rat)
PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE-38 (16-38),HUMAN,OVINE,RAT
PACAP-38 (16-38),HUMAN,OVINE,RAT
PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE (16-38) (HUMAN,OVINE,RAT)
GLN-MET-ALA-VAL-LYS-LYS-TYR-LEU-ALA-ALA-VAL-LEU-GLY-LYS-ARG-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2: QMAVKKYLAAVLGKRYKQRVKNK-NH2
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