Introduction：Basic information about CAS 85465-82-3|Thymopoietin II: 32-34, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Thymopoietin II: 32-34 |
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| CAS Number | 85465-82-3 | Molecular Weight | 417.46100 |
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| Density | 1.51g/cm3 | Boiling Point | / |
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| Molecular Formula | C16H31N7O6 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | (2S)-2-[[(2S)-6-amino-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]butanedioic acid |
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| Synonym | More Synonyms |
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Thymopoietin II: 32-34 BiologicalActivity
| Description | Thymotrinan (RGH-0205) is a biologically active fragment of the naturally occurring thymus hormone thymopoietin and a immunomodulating peptide. Thymotrinan exerts similar immunomodulatory activities to TP5 and to affect humoral as well as cellular responses[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| References | [1]. Heizmann J, et al. Enzymatic cleavage of thymopoietin oligopeptides by pancreatic and intestinal brush-border enzymes. Peptides. 1996;17(7):1083-1089. |
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Chemical & Physical Properties
| Density | 1.51g/cm3 |
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| Molecular Formula | C16H31N7O6 |
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| Molecular Weight | 417.46100 |
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| Exact Mass | 417.23400 |
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| PSA | 246.74000 |
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| LogP | 0.60820 |
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| Index of Refraction | 1.633 |
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| InChIKey | MJINRRBEMOLJAK-DCAQKATOSA-N |
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| SMILES | NCCCCC(NC(=O)C(N)CCCN=C(N)N)C(=O)NC(CC(=O)O)C(=O)O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- CI9099033
- CHEMICAL NAME :
- L-Aspartic acid, N-(N(sup 2)-L-arginyl-L-lysyl)-
- CAS REGISTRY NUMBER :
- 85465-82-3
- LAST UPDATED :
- 199407
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C16-H31-N7-O6
- MOLECULAR WEIGHT :
- 417.54
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 11,764,1986
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 11,764,1986
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 11,764,1986
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Synonyms
| Rgh 0205 |
| Thymotrinanum [INN-Latin] |
| Arg-Lys-Asp |
| Thymotrinanum |
| N-(N(sup 2)-L-Arginyl-L-lysyl)-L-aspartic acid |
| Timotrinan |
| Timotrinan [INN-Spanish] |
| L-Aspartic acid,N-(N(sup 2)-L-arginyl-L-lysyl) |
| Thymotrinan |
| Thymopoietin II: 32-34 |
