CAS 5936-28-7|(+)-B-HYDRASTINE HCL
Introduction：Basic information about CAS 5936-28-7|(+)-B-HYDRASTINE HCL, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (+)-B-HYDRASTINE HCL | ||
|---|---|---|---|
| CAS Number | 5936-28-7 | Molecular Weight | 419.85500 |
| Density | / | Boiling Point | 548.8ºC at 760 mmHg |
| Molecular Formula | C21H22ClNO6 | Melting Point | 115ºC |
| MSDS | / | Flash Point | 285.7ºC |
Names
| Name | (+)-b-hydrastine hcl |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Boiling Point | 548.8ºC at 760 mmHg |
|---|---|
| Melting Point | 115ºC |
| Molecular Formula | C21H22ClNO6 |
| Molecular Weight | 419.85500 |
| Flash Point | 285.7ºC |
| Exact Mass | 419.11400 |
| PSA | 66.46000 |
| LogP | 3.61310 |
| InChIKey | URBFHJWLYXILMP-VOMIJIAVSA-N |
| SMILES | COc1ccc2c(c1OC)C(=O)OC2C1c2cc3c(cc2CCN1C)OCO3.Cl |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,57,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1270 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,57,1969
Safety Information
| Hazard Codes | Xn |
|---|---|
| Risk Phrases | 22 |
| Safety Phrases | 36 |
| RIDADR | UN 1544 |
| RTECS | MU6125000 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
Articles24
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| Differential modulation of respiratory neuronal discharge patterns by GABA(A) receptor and apamin-sensitive K(+) channel antagonism. J. Neurophysiol. 86(5) , 2363-73, (2001) The discharge patterns of respiratory neurons of the caudal ventral respiratory group (cVRG) appear to be subject to potent GABAergic gain modulation. Local application of the GABA(A) receptor antagon... | |
| Effects of (1R,9S)-beta-hydrastine on l-DOPA-induced cytotoxicity in PC12 cells. Eur. J. Pharmacol. 488(1-3) , 71-7, (2004) (1R,9S)-beta-Hydrastine in lower concentrations of 10-50 microM inhibits dopamine biosynthesis in PC12 cells. In this study, the effects of (1R,9S)-beta-hydrastine on L-DOPA (L-3,4-dihydroxyphenylalan... |
Synonyms
| ISOCORYNE HYDROCHLORIDE |
| (1R,9S)-B-hydrastine hydrochloride |
| HydrastineHCl |
| HYDRASTINE HCL,(+)-B |
| HYDRASTINE HCl,(+)-B-(P) |
| (S)-6,7-dimethoxy-3-((R)-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-isobenzofuran-1-one,hydrochloride |
| HYDRASTINE HYDROCHLORIDE |
