Introduction：Basic information about CAS 5943-62-4|Tetraethyl decane-1,10-diylbis(phosphonate), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Tetraethyl decane-1,10-diylbis(phosphonate) |
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| CAS Number | 5943-62-4 | Molecular Weight | 414.45400 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C18H40O6P2 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 1,10-bis(diethoxyphosphoryl)decane |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | Tetraethyl decane-1,10-diylbis(phosphonate) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | Alkyl-Chain |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Molecular Formula | C18H40O6P2 |
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| Molecular Weight | 414.45400 |
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| Exact Mass | 414.23000 |
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| PSA | 90.68000 |
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| LogP | 6.63940 |
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| InChIKey | JSLDHSYSRUFYMI-UHFFFAOYSA-N |
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| SMILES | CCOP(=O)(CCCCCCCCCCP(=O)(OCC)OCC)OCC |
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Synonyms
| 1,10-Bis-(O,O-diethyl-phosphono)-decan |
| Decan-diphosphonsaeure-(1,10)-tetraethylester |
| tetraethyl decane-1,10-diyldiphosphonate |
| TETRAETHYL DECAMETHYLENEDIPHOSPHONATE |
| Decamethylen-bis-(diethylphosphonat) |
| tetra-ethyl decylene diphosphonate |
