CAS 51165-09-4|Substance P (5-11) trifluoroacetate salt

Introduction：Basic information about CAS 51165-09-4|Substance P (5-11) trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Substance P (5-11) trifluoroacetate salt BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Substance P (5-11) trifluoroacetate salt
CAS Number	51165-09-4	Molecular Weight	869.04200
Density	1.265g/cm3	Boiling Point	1375.5ºC at 760 mmHg
Molecular Formula	C₄₁H₆₀N₁₀O₉S	Melting Point	/
MSDS	/	Flash Point	785.6ºC

Names

Name	substance p (5-11)
Synonym	More Synonyms

Substance P (5-11) trifluoroacetate salt BiologicalActivity

Description	Substance P (5-11), the C-terminal heptapeptide of Substance P (Substance P (HY-P0201)), is a neuropeptide. Substance P (5-11) binds to NK-1 tachykinin receptor[1].
Related Catalog	Signaling Pathways >>Neuronal Signaling >>Neurokinin ReceptorResearch Areas >>Neurological DiseaseSignaling Pathways >>GPCR/G Protein >>Neurokinin Receptor
In Vitro	当将富含神经胶质细胞的兔脑部分与 [3H]Substance P (5-11) 一起孵育时，观察到 [3H]Substance P (5-11) 的摄取。当 Substance P 从神经末梢释放时，它被水解成 Substance P (5-11)，后者又积聚到神经胶质细胞和神经末梢，这种高亲和力摄取机制可能在终止突触过程中发挥重要作用[1]。
References	[1]. A Inoue, et al. Active uptake system for substance P carboxy-terminal heptapeptide (5-11) into a fraction from rabbit enriched in glial cells. Jpn J Pharmacol. 1984 Oct;36(2):137-45.

Chemical & Physical Properties

Density	1.265g/cm3
Boiling Point	1375.5ºC at 760 mmHg
Molecular Formula	C₄₁H₆₀N₁₀O₉S
Molecular Weight	869.04200
Flash Point	785.6ºC
Exact Mass	868.42700
PSA	355.19000
LogP	3.30140
Index of Refraction	1.581
InChIKey	FHHJIELOJQJHCG-JNRWAQIZSA-N
SMILES	CSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=O)C(CCC(N)=O)NC(=O)C(N)CCC(N)=O)C(N)=O

Synonyms

L-Gln-L-Gln-L-Phe-L-Phe-Gly-L-Leu-L-Met-NH2

Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2

L-Glu(NH2)-L-Glu(NH2)-L-Phe-L-Phe-Gly-L-Leu-L-Met-NH2

H-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2

HEPTA-SUBSTANCE P

Substance-P-(5-11) Hepta-Substance P

substance P fragment 5-11

substance P5-11

Recommended......