Introduction：Basic information about CAS 123-25-1|Diethyl succinate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Diethyl succinate |
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| CAS Number | 123-25-1 | Molecular Weight | 174.194 |
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| Density | 1.0±0.1 g/cm3 | Boiling Point | 218.4±8.0 °C at 760 mmHg |
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| Molecular Formula | C8H14O4 | Melting Point | -20 °C |
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| MSDS | ChineseUSA | Flash Point | 90.6±0.0 °C |
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Names
| Name | Diethyl succinate |
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| Synonym | More Synonyms |
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Diethyl succinate BiologicalActivity
| Description | Diethyl succinate (Diethyl Butanedioate) is used at physiological pH and crosses biological membranes, incorporates into cells in tissue culture and is metabolized by the TCA cycle. Diethyl succinate is known to be non-toxic and used in fragrances and flavoring[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
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| References | [1]. Zacharias NM, et al. Real-time molecular imaging of tricarboxylic acid cycle metabolism in vivo by hyperpolarized 1-(13)C diethyl succinate. J Am Chem Soc. 2012 Jan 18;134(2):934-43. |
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Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
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| Boiling Point | 218.4±8.0 °C at 760 mmHg |
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| Melting Point | -20 °C |
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| Molecular Formula | C8H14O4 |
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| Molecular Weight | 174.194 |
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| Flash Point | 90.6±0.0 °C |
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| Exact Mass | 174.089203 |
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| PSA | 52.60000 |
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| LogP | 1.26 |
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| Vapour density | 6 (vs air) |
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| Vapour Pressure | 0.1±0.4 mmHg at 25°C |
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| Index of Refraction | 1.423 |
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| InChIKey | DKMROQRQHGEIOW-UHFFFAOYSA-N |
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| SMILES | CCOC(=O)CCC(=O)OCC |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- WM7400000
- CHEMICAL NAME :
- Succinic acid, diethyl ester
- CAS REGISTRY NUMBER :
- 123-25-1
- BEILSTEIN REFERENCE NO. :
- 0907645
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C8-H14-O4
- MOLECULAR WEIGHT :
- 174.22
- WISWESSER LINE NOTATION :
- 2OV2VO2
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,707,1978
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rat
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,707,1978
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,374,1986 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8530 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3671 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 82 (estimated) No. of Female Employees: 14 (estimated)
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US) |
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| Hazard Codes | Xi |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S26-S36-S24/25-S22 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 2 |
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| RTECS | WM7400000 |
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| HS Code | 29171990 |
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Customs
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Synonyms
| succinic acid diethyl ester |
| Butanedioic acid diethyl ester |
| EINECS 204-612-0 |
| MFCD00009208 |
| Butamedioic acid diethyl ester |
| Diethyl Butanedioate |
| Butanedioic acid, diethyl ester |
| diethyl butane-1,4-dioate |
| Diethyl succinate |
| Ethyl Succinate |
