CAS 140-87-4|Cyanoacetohydrazide
Introduction：Basic information about CAS 140-87-4|Cyanoacetohydrazide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Cyanoacetohydrazide | ||
|---|---|---|---|
| CAS Number | 140-87-4 | Molecular Weight | 99.091 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 405.6±28.0 °C at 760 mmHg |
| Molecular Formula | C3H5N3O | Melting Point | 108-110 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 199.1±24.0 °C |
| Symbol | GHS06 | Signal Word | Danger |
Names
| Name | Cyanoacetohydrazide |
|---|---|
| Synonym | More Synonyms |
Cyanoacetohydrazide BiologicalActivity
| Description | Cyanoacetohydrazide is an anti-TB drug. |
|---|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>Infection |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 405.6±28.0 °C at 760 mmHg |
| Melting Point | 108-110 °C(lit.) |
| Molecular Formula | C3H5N3O |
| Molecular Weight | 99.091 |
| Flash Point | 199.1±24.0 °C |
| Exact Mass | 99.043259 |
| PSA | 78.91000 |
| LogP | -2.16 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.480 |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 228 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 21,635,1968
Safety Information
| Symbol | GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H312-H315-H319-H332-H335 |
| Precautionary Statements | P261-P280-P301 + P310-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R20/21/22;R36/37/38 |
| Safety Phrases | S26-S28-S36/37/39-S45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | AG4200000 |
| Packaging Group | I; II; III |
| Hazard Class | 6.1 |
| HS Code | 2928000090 |
Customs
| HS Code | 2928000090 |
|---|---|
| Summary | 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |
Articles3
More Articles| Internal vibrations of a molecule consisting of rigid segments. I. Non-interacting internal vibrations. Acta Crystallogr. A 49 ( Pt 1) , 10-22, (1993) For molecular crystals, a procedure is proposed for interpreting experimentally determined atomic mean square anisotropic displacement parameters (ADPs) in terms of the overall molecular vibration tog... | |
| Cyanoacetic acid hydrazones of 3-(and 4-)acetylpyridine and some derived ring systems as potential antitumor and anti-HCV agents. Arch. Pharm. (Weinheim) 339(1) , 14-23, (2006) Two new acetylpyridinehydrazones derived from cyanoacetic acid hydrazide have been synthesized namely: cyanoacetic acid (1-pyridin-3 or 4-yl-ethylidene) hydrazides (1a,b). and some derived ring system... | |
| The reaction of digitoxin and digoxin with cyanoacetic acid hydrazide: synthesis of coumarin, thiazole, thiophene and pyridine derivatives with potential biological activities. Arch. Pharm. Res. 24(5) , 377-84, (2001) The reaction of either Digitoxin or Digoxin with cyanoacetic acid hydrazide gave the hydrazone derivatives 3a and 3b respectively. The reactivity of the latter products towards chemical reagents was s... |
Synonyms
| UNII-40H59YCS67 |
| Cyacetacide |
| EINECS 205-437-2 |
| Armazal |
| Cyanoacetylhydrazine |
| Dictycide |
| Cyanoacetic Acid Hydrazide |
| MFCD00007611 |
| Neohydrazid |
| Cyanoacetic Hydrazide |
| a-Cyanoacetohydrazide |
| Dictyzide |
| 2-Cyanoacetohydrazide |
| Hidacian |
| Acetic acid, 2-cyano-, hydrazide |
| Leandin |
| Malononitrile hydrazide |
