CAS 119-67-5|2-Carboxybenzaldehyde
Introduction：Basic information about CAS 119-67-5|2-Carboxybenzaldehyde, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Carboxybenzaldehyde | ||
|---|---|---|---|
| CAS Number | 119-67-5 | Molecular Weight | 150.13 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 321.8±25.0 °C at 760 mmHg |
| Molecular Formula | C8H6O3 | Melting Point | 94-96 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 162.6±19.7 °C |
Names
| Name | 2-formylbenzoic acid |
|---|---|
| Synonym | More Synonyms |
2-Carboxybenzaldehyde BiologicalActivity
| Description | 2-Carboxybenzaldehyde is a chemical compound. 2-Carboxybenzaldehyde consists of a benzene ring, with an aldehyde and a carboxylic acid as substituents that are ortho to each other. 2-Carboxybenzaldehyde can be used to form ligands with metal ions. Ni(II) and Cu(II) complexes of 2-Carboxybenzaldehyde thiosemicarbazone has anticancer and antibacterial activities[1]. |
|---|---|
| Related Catalog | Research Areas >>CancerResearch Areas >>InfectionSignaling Pathways >>Others >>Others |
| References | [1]. Chandra S, et al. Synthesis, spectroscopic, anticancer and antibacterial studies of Ni(II) and Cu(II) complexes with 2-carboxybenzaldehyde thiosemicarbazone. Spectrochim Acta A Mol Biomol Spectrosc. 2014;129:333-338. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 321.8±25.0 °C at 760 mmHg |
| Melting Point | 94-96 °C(lit.) |
| Molecular Formula | C8H6O3 |
| Molecular Weight | 150.13 |
| Flash Point | 162.6±19.7 °C |
| Exact Mass | 150.031693 |
| PSA | 54.37000 |
| LogP | 0.77 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.620 |
| InChIKey | DYNFCHNNOHNJFG-UHFFFAOYSA-N |
| SMILES | O=Cc1ccccc1C(=O)O |
| Water Solubility | soluble |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 27,665,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2430 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 27,665,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4480 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 27,665,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1860 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 27,665,1974
Safety Information
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
|---|---|
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36-S24/25 |
| RIDADR | PG2 |
| WGK Germany | 2 |
| RTECS | TH7015000 |
| HS Code | 29183000 |
Customs
| HS Code | 2918300090 |
|---|---|
| Summary | 2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
Articles3
More Articles| Highly efficient synthesis of N-substituted isoindolinones and phthalazinones using Pt nanowires as catalysts. Org. Lett. 14(7) , 1876-9, (2012) A series of N-substituted isoindolinones have been successfully synthesized through the reductive C-N coupling and intramolecular amidation of 2-carboxybenzaldehyde and amines. This one-pot synthesis ... | |
| Degradation of fluoranthene by Pasteurella sp. IFA and Mycobacterium sp. PYR-1:isolation and identification of metabolites. J. Appl. Microbiol. 85(4) , 746-54, (1998) The findings from a biodegradability study of fluoranthene using two pure bacterial strains, Pasteurella sp. IFA (B-2) and Mycobacterium sp. PYR-1 (AM) are reported. Of total fluoranthene, 24% (B-2) a... | |
| Degradation of phenanthrene by the rhizobacterium Ensifer meliloti. Biodegradation 25(6) , 787-95, (2014) The biodegradation of the polycyclic aromatic hydrocarbon phenantherene by the rhizobacterial strain Ensifer meliloti P221, isolated from the root zone of plant grown in PAH-contaminated soil was stud... |
Synonyms
| Phthalaldehydic Acid |
| Benzoic acid, 2-formyl- |
| EINECS 204-342-3 |
| Benzaldehyde-2-carboxylic Acid |
| 2-carboxybenzaldehyde |
| 2-Formylbenzoic acid |
| MFCD00003336 |
| 2-Formyl-benzoic acid |
