Introduction：Basic information about CAS 150322-05-7|5-Carboxytetramethylrhodamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5-Carboxytetramethylrhodamine |
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| CAS Number | 150322-05-7 | Molecular Weight | 430.453 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C25H22N2O5 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 3',6'-bis(dimethylamino)-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-carboxylic acid |
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| Synonym | More Synonyms |
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5-Carboxytetramethylrhodamine BiologicalActivity
| Description | 5-Carboxytetramethylrhodamine can be used as a fluorescent probe of nucleic acids and proteins. 5-Carboxytetramethylrhodamine displays excitation maxima of 558 nm and an emission maximum of 586 nm[1][2][3]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. Lyu Z, et al. Steric-Free Bioorthogonal Labeling of Acetylation Substrates Based on a Fluorine-Thiol Displacement Reaction. J Am Chem Soc. 2021 Jan 27;143(3):1341-1347. [2]. Bucevičius J, et al. Rhodamine-Hoechst positional isomers for highly efficient staining of heterochromatin. Chem Sci. 2018 Dec 12;10(7):1962-1970. [3]. Lyttle MH, et al. A tetramethyl rhodamine (Tamra) phosphoramidite facilitates solid-phase-supported synthesis of 5'-Tamra DNA. J Org Chem. 2000 Dec 29;65(26):9033-8. |
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Chemical & Physical Properties
| Molecular Formula | C25H22N2O5 |
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| Molecular Weight | 430.453 |
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| Exact Mass | 430.152863 |
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| PSA | 97.05000 |
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| LogP | 3.72780 |
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| InChIKey | DCVXPZDNLDPUES-UHFFFAOYSA-N |
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| SMILES | CN(C)c1ccc2c(c1)Oc1cc(N(C)C)ccc1C21OC(=O)c2cc(C(=O)O)ccc21 |
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Safety Information
Synonyms
| 5-carboxy Tamra |
| 5-TAMRA |
| 5-carboxytetramethylrhodamine |
| Xanthylium, 9-(2,4-dicarboxyphenyl)-3,6-bis(dimethylamino)-, inner salt |
| 2-[3,6-Bis(dimethylamino)-9-xantheniumyl]-5-carboxybenzoate |
