Introduction：Basic information about CAS 35095-93-3|2-AMINO-6-CHLORO-9-(3,5-DI-O-(P-TOLUOYL)-BETA-D-2-DEOXYRIBOFURNANOSYL)PURINE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-AMINO-6-CHLORO-9-(3,5-DI-O-(P-TOLUOYL)-BETA-D-2-DEOXYRIBOFURNANOSYL)PURINE |
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| CAS Number | 35095-93-3 | Molecular Weight | 521.95 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C26H24ClN5O5 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2-AMINO-6-CHLORO-9-(3,5-DI-O-(P-TOLUOYL)-β-D-2-DEOXYRIBOFURNANOSYL)PURINE |
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BiologicalActivity
| Description | 2-Amino-6-chloropurine-9-beta-D-(2’-deoxy-3’,5’-di-O-(p-toluoyl))riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Molecular Formula | C26H24ClN5O5 |
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| Molecular Weight | 521.95 |
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| Exact Mass | 521.14700 |
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| PSA | 131.45000 |
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| LogP | 4.63000 |
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| InChIKey | HUDUPJKATQIHAF-XUVXKRRUSA-N |
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| SMILES | Cc1ccc(C(=O)OCC2OC(n3cnc4c(Cl)nc(N)nc43)CC2OC(=O)c2ccc(C)cc2)cc1 |
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